Richard Pierce

Richard Pierce, MD, is an Associate Professor of Pediatrics (Critical Care) at Yale School of Medicine. He specializes in pediatric critical care medicine, focusing on vascular dysfunction and translational research. His clinical roles include Associate Program Director for the Pediatric Critical Care Medicine Fellowship and Co-Director of the Mentored Clinical Experience for the Medical Research Training Program.

Education & Training:

• MD and MS in Organic Chemistry (University of Illinois at Urbana-Champaign)
• Pediatric Residency (Connecticut Children's Medical Center, 2013)
• Pediatric Critical Care Fellowship (Yale University, 2016)

Research Interests:

• Vascular dysfunction in critical illness, particularly capillary leak syndrome and endothelial permeability
• Single-cell transcriptomics of critically ill pediatric patients
• Translational studies targeting blood vessel dysfunction in acute lung injury and sepsis
• Genomic approaches via the Yale Pediatric Genomics Discovery Program

Key Contributions:

• Discovered RhoB's role in systemic capillary leak syndrome via p190BRhoGAP mutations
• Developed AI-driven patient triage platforms for viral outbreaks
• Leads studies on endothelial gene networks and microRNA-1's protective effects in lung injury

Awards & Recognition:

• National Institutes of Health Loan Repayment Program (2015-2018)
• Young Investigator Coaching Award (Society for Pediatric Research, 2018)
• Howard Pearson Pediatric Faculty Teaching Award (Yale School of Medicine, 2018)

Labs & Affiliations:

• Pierce Lab (focused on vascular biology and critical care research)
• Yale's Center for Infection and Immunity
• Program in Translational Biomedicine