Pavel Bashtrykov

Pavel Bashtrykov is a Researcher at the University of Stuttgart's Institute of Biochemistry and Technical Biochemistry, part of the Faculty of Chemistry. His work focuses on epigenetic mechanisms, DNA methylation, and histone modifications. He contributes to interdisciplinary research projects such as the Collaborative Research Center (SFB) 1333 on catalysis in confined geometries. His research integrates biochemistry, molecular biology, and advanced analytical techniques to elucidate epigenetic regulation and its implications in health and disease.

Key research interests include allele-specific epigenome editing, DNA methyltransferase specificity, and the interplay between histone modifications and DNA methylation. His studies often involve cutting-edge tools like CRISPR/dCas9 systems and fluorescent biosensors for locus-specific analysis. Recent work addresses oncogenic TERT promoter mutations and their epigenetic targeting, as well as the role of adherens junctions in modulating DNA methylation patterns.

Bashtrykov collaborates on EU-funded projects and leverages computational models to inform molecular design. His contributions span basic science to translational applications, including epigenetic therapies and biomarker discovery.