Olwyn Mahon

Olwyn Mahon is a Research Fellow at the School of Engineering, University of Limerick, affiliated with the Limerick Digital Cancer Research Centre. Her research integrates biomedical engineering with cancer therapeutics and regenerative medicine, focusing on biomaterial-tissue interactions in pathological and healing contexts.

Her core research interests span tissue engineering, immunology, biomaterials science, cancer biology, and bone regeneration. She investigates macrophage polarization dynamics in response to engineered biomaterials, extracellular matrix remodeling in tumor microenvironments, and the development of advanced scaffolds for bone repair. Key methodologies include nanoparticle drug delivery systems, 3D tumor-bone models, and macrophage metabolic profiling.

Analysis of her 2021-2025 publications reveals a cohesive trajectory toward translational cancer-bone interface solutions. Recurring themes include osteosarcoma-targeted nanotherapies, biomaterial-induced immunomodulation, and dual-function platforms addressing both tumor suppression and tissue regeneration. Her work consistently bridges fundamental immunology with clinical engineering applications.

Dr. Mahon actively contributes to the Limerick Digital Cancer Research Centre's interdisciplinary ecosystem, collaborating with clinicians and material scientists to develop digital tools for cancer diagnostics and biomaterial-based regenerative therapies. Her network spans immunology, oncology, and advanced manufacturing domains as evidenced by multi-institutional co-authorships.