Niall Macquaide

Dr. Niall Macquaide is an Honorary Lecturer in the School of Cardiovascular & Metabolic Health at Caledonian University. His research focuses on calcium signaling in cardiac myocytes, cardiac electrophysiology, and mechanisms underlying heart failure. He has contributed extensively to studies on ryanodine receptor (RyR) function, calcium handling defects, and arrhythmia triggers. His work employs advanced imaging techniques like super-resolution microscopy and computational modeling to explore cellular-level mechanisms.

Key areas of investigation include Ryanodine receptor clustering and dispersion, calcium transients in cardiac dysfunction, and the role of post-translational modifications (e.g., palmitoylation, SUMOylation) in ion channel regulation. Dr. Macquaide has collaborated on studies involving rabbit, rat, and human cardiac tissue models, addressing topics like ventricular arrhythmias, myocardial infarction effects, and atrial fibrillation mechanisms.

His publications span high-impact journals such as Proceedings of the National Academy of Sciences, Cardiovascular Research, and Journal of Molecular and Cellular Cardiology. While no formal awards are listed, his research has implications for understanding and treating cardiac arrhythmias and heart failure.