
About
Prof. Dr. Melanie Mark is a faculty member at Ruhr University Bochum, affiliated with the Faculty of Biology and Biotechnology and the Department of General Zoology and Neurobiology. She leads the Behavioral Neurobiology Group, focusing on the cerebellum's role in neurological disorders like ataxia, stress-induced dystonia, and absence epilepsy, as well as the serotonergic system's regulation of aggression and cerebellar contributions to fear and anxiety.
- Research Highlights:
- Developed transgenic mouse models for Episodic Ataxia type 2 and Spinocerebellar Ataxia type 6.
- Investigated RGS2 overexpression and P/Q-type calcium channel knockout in serotonergic neurons to study aggression.
- Explored cerebellar mechanisms in fear conditioning using optogenetics and pharmacology.
- Academic Contributions:
- Active in teaching (e.g., courses in Behavioral Neurobiology, Neuroscience, and Experimental Medicine).
- Collaborates with the International Graduate School of Neuroscience and Research Department of Neuroscience.
- Techniques:
- Optogenetics
- Genetic modeling
- Pharmacology
- Synaptic transmission analysis
Email: melanie.mark@ruhr-uni-bochum.de | ORCID
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