Matteo Dal Peraro

Matteo Dal Peraro is an Associate Professor at École polytechnique fédérale de Lausanne (EPFL) in the School of Life Sciences, where he leads the Laboratory for Biomolecular Modeling (LBM) within the Interfaculty Institute of Bioengineering (IBI). He also holds significant administrative roles as Head of IBI-SV Administration and Co-Director of IBI-STI Administration, demonstrating his leadership across both the School of Life Sciences and School of Engineering. His research bridges computational approaches with experimental validation to understand complex biological systems at multiple scales.

His educational background includes a B.S. and M.S. in Physics from the University of Padua (2000), followed by a Ph.D. in Biophysics from the International School for Advanced Studies (SISSA) in Trieste (2004). He then completed postdoctoral training at the University of Pennsylvania under Professor M. L. Klein before joining EPFL as a Tenure Track Assistant Professor in late 2007.

Dal Peraro's research focuses on computational biophysics and multiscale modeling of biological systems, with particular emphasis on membrane-protein interactions, nanopore sensing technologies, and structural biology. His work spans fundamental molecular mechanisms to applied educational technologies, demonstrating a commitment to both scientific discovery and knowledge dissemination. He has made significant contributions to understanding protein-membrane interactions, antibiotic resistance mechanisms, mitochondrial disorders, and viral pathogenesis through advanced computational approaches.

His publication record shows a strong trend toward integrating augmented and virtual reality technologies with molecular modeling, exemplified by his development of the moleculARweb platform for chemistry and structural biology education. His research spans computational methods development, structural characterization of biomolecules, membrane biophysics, and applications to medically relevant problems including antibiotic resistance and neurodegenerative disorders. This interdisciplinary approach connects fundamental biophysical principles with practical applications in medicine and education.

Dal Peraro has mentored numerous doctoral students through EPFL's PhD programs, particularly in Computational and Quantitative Biology. His leadership extends to serving on PhD program committees and directing research groups focused on computational molecular biology. He has established collaborations across multiple disciplines, facilitating integrative approaches to complex biological problems.

He leads the Laboratory for Biomolecular Modeling (LBM), which develops and applies computational methods to study biological systems at multiple scales. The lab bridges molecular simulations with experimental validation, creating a synergistic approach to understanding complex biological phenomena. Dal Peraro's team has made significant contributions to membrane biophysics, protein folding, and the development of educational technologies that make structural biology accessible through augmented reality platforms.