Juan Francisco Bada Juarez

Juan Francisco Bada Juarez is a Scientist at the École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the Prof. Dal Peraro Group within the Institute of Bioengineering (IBI-SV). His research focuses on structural biology, membrane proteins, and nanopore technology, particularly leveraging lipid-based systems like lipodisq nanoparticles for protein stabilization and drug delivery. He contributes to innovative methods for detergent-free membrane protein extraction and high-resolution structural characterization.

His work integrates experimental and computational approaches, including single-molecule detection with biological nanopores and deep learning-assisted analysis. Key projects involve engineering aerolysin-based nanopores for biosensing, dissecting membrane association mechanisms of pore-forming toxins, and developing light-sensitive membrane proteins for dynamic studies. He is based at EPFL’s School of Basic Sciences, contributing to interdisciplinary research at the intersection of biophysics and nanotechnology.

Juan’s lab investigates applications of structural biology to antimicrobial peptides, drug delivery systems, and protein engineering, with a focus on maintaining protein functionality in native-like environments. His research has advanced understanding of protein-membrane interactions, enabling breakthroughs in biomolecular detection and therapeutic delivery mechanisms.