About
Mark Kelly, PhD is a Professional Researcher at the University of California, San Francisco (UCSF) within the School of Pharmacy. His research spans interdisciplinary domains including neurology, molecular biology, biochemistry, and pharmaceutical chemistry, with a focus on autoimmune encephalitis, protein design, and metabolic disease mechanisms.
- Develops computational methods for protein engineering
- Investigates autoimmune neurological disorders like CASPR2/LGI1-antibody encephalitis
- Conducts cross-disciplinary work in metabolic diseases (NASH, mitochondrial function)
- Applies machine learning to molecular design challenges
- Active in biomedical imaging and cellular transport mechanisms
His recent publications highlight collaborations with UCSF colleagues like Tanja Kortemme and Danica Galonic Fujimori, with significant work in Science, Cell, and JAMA Neurology. Notable contributions include computational protein design methodology and neuroimmunology research.
While no formal awards or student advisement details are listed in this profile, his work has been cited in multiple high-impact journals and shared across academic networks. Kelly's research bridges structural biology with clinical applications, particularly in neurodegenerative and metabolic diseases.
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