Lei Xing

Lei Xing is an Assistant Professor in the Department of Biological Sciences at the University of Manitoba's Faculty of Science. His research focuses on understanding how placental factors regulate neural stem cell behavior during neocortex development, using multidisciplinary approaches combining bioinformatics, molecular techniques, and advanced imaging. He employs genetically modified mice and 3D organoids to study cellular and molecular mechanisms underlying human brain development and neurodevelopmental disorders like Autism Spectrum Disorder. The Xing Lab actively recruits motivated students and postdocs.

Research Interests:

• Neural stem cell proliferation/differentiation
• Human neocortex evolution
• Neurodevelopmental disorder mechanisms
• Stem cell-derived organoid models

Publications highlight investigations into metabolic pathways, neurotransmitter regulation, and evolutionary genetic factors impacting brain development. Collaborations involve cutting-edge tools like transcriptome analysis and proteomic profiling to address neurobiological questions.