Lawrence Goldfinger

Lawrence Goldfinger serves as Professor in the Department of Medicine at Thomas Jefferson University's College of Life Sciences and directs the Molecular Physiology & Translational Medicine PhD Program, conducting research at the Cardeza Center for Hematologic Research.

Education:

• PhD, Carnegie Mellon University

Research Interests: Dr. Goldfinger investigates molecular mechanisms of platelet function in hemostasis and thrombosis through integrated studies of gene expression, cell biology, and physiological modeling. His work targets therapeutic modulation of platelet activity with emphasis on translational applications for clotting disorders.

Publication Trends: Recent articles demonstrate consistent focus on platelet-megakaryocyte molecular regulation, featuring RUNX1/Argonaute2 pathways, sex-specific protein expression, and nanoparticle-based antithrombotics that minimize bleeding risks. Key themes include microRNA-mediated reactivity control and molecular trafficking mechanisms.

Laboratory: He leads research operations at the Cardeza Center for Hematologic Research, where his team explores fundamental platelet biology and pre-clinical therapeutic development.