A. Koneti Rao

A. Koneti Rao, MD is a Professor in the Department of Pathology and Laboratory Medicine at Thomas Jefferson University's Lewis Katz School of Medicine. He serves as Co-Director and holds the Sol Sherry Professorship at the Sol Sherry Thrombosis Research Center. His work bridges clinical and molecular hemostasis research.

• MBBS, All India Institute of Medical Sciences (1973)
• Internship, Albert Einstein Medical Center (1975)
• Residency, Thomas Jefferson University Hospital (1977)
• Fellowships in Hematology/Oncology (Temple University) and Hematology (Cardeza Foundation).

Rao's research focuses on molecular mechanisms in inherited platelet disorders, particularly the role of RUNX1 transcription factor in regulating genes like MYL9, ALOX12, PF4, and PRKCQ. His work connects platelet dysfunction to cardiovascular events and explores hyperglycemia/hyperinsulinemia's impact on tissue factor pathways in diabetes. Current studies aim to identify novel antiplatelet targets and understand thrombosis in metabolic disorders.

His article trends reveal RUNX1 as a central regulator of platelet gene expression, with implications for clot stability, endosomal trafficking, and cardiovascular risk. Collaborative studies with Dr. Guenther Boden highlight diabetes' procoagulant effects.

• Institute Prize for Distinction in Pharmacology

Rao has received NIH and March of Dimes funding. His team at the Sol Sherry Thrombosis Research Center investigates transcriptional regulation of platelet proteins and coagulation activation in metabolic and hematological diseases.