Lan Guo

Lan Guo is an Associate Research Professor at the University of Kansas School of Pharmacy, where they focus on Alzheimer's disease research. Their work explores the pathogenesis of this neurodegenerative disorder, particularly examining the role of neuronal-microglial crosstalk in disease progression and employing multidisciplinary approaches including molecular neurobiology, live cell imaging, and transcriptomics.

Dr. Guo received their educational training at Shandong University in China, earning a B.S. and M.D. in Medicine in 2000, followed by a Ph.D. in Pathogenic Biology in 2006.

Dr. Guo's research program centers on deciphering the mechanisms of Alzheimer's disease, with particular emphasis on how mitochondrial dysfunction contributes to synaptic failure and cognitive decline. Their work spans from basic molecular mechanisms to potential therapeutic interventions, with growing interest in the intersection of endocrinology, neuroinflammation, and neurodegeneration. Recent publications reveal consistent focus on pathways involving cyclophilin D, amyloid-beta, and neuronal-microglial communication.

Dr. Guo has published extensively in high-impact journals including Nature Medicine, Proceedings of the National Academy of Sciences, Nature Communications, and Journal of Neuroscience, demonstrating sustained productivity and scholarly impact in the Alzheimer's research field.

As part of their academic role, Dr. Guo likely participates in graduate education within the Pharmacology & Toxicology program at KU, contributing to the training of future neuroscientists and pharmacologists through research mentorship and potentially classroom instruction.