Kyle Flippo

Kyle Flippo is an Assistant Professor at the University of Iowa Carver College of Medicine, affiliated with both the Department of Internal Medicine-Endocrinology and Metabolism and the Department of Neuroscience and Pharmacology. His research bridges metabolic regulation and neurobiology, focusing on mitochondrial dynamics, FGF21 signaling, and hypothalamic circuits controlling energy homeostasis.

• Education: PhD in Pharmacology (University of Iowa), Postdoctoral Research Scholar (Neuroscience & Pharmacology, University of Iowa)
• Affiliations: Fraternal Order of Eagles Diabetes Research Center, Iowa Neuroscience Institute

Flippo's research explores how fibroblast growth factor 21 (FGF21) modulates neuronal activity to influence metabolism, addiction, and neuroprotection. His work on tanycytes, glutamatergic neurons, and mitochondrial dynamics has advanced understanding of metabolic disorders and neurological diseases.

Recent publications highlight his contributions to FGF21's role in dietary regulation, alcohol consumption suppression, and neuroprotective mechanisms via Drp1 inhibition. His studies often integrate genetic models, transcriptomics, and behavioral assays.

As head of the Flippo Laboratory, he mentors trainees in molecular medicine and participates in predoctoral and postdoctoral programs, including the Pain Research Program and Training Grants in Pharmacological Sciences.