About
Dr. Karolina Rygiel is a researcher at Newcastle University specializing in mitochondrial genetics and its role in degenerative diseases. She has collaborated extensively with multidisciplinary teams across molecular biology, neurology, and pathology departments.
Her research focuses on mitochondrial DNA deletions, respiratory chain deficiencies, and their implications in conditions such as inclusion body myositis, Parkinson's disease, and sarcopenia. Key methodologies include single-cell analysis, immunofluorescence assays, and real-time PCR techniques.
Her work spans comparative aging studies (e.g., naked mole-rats) and human disease models, emphasizing the interplay between mitochondrial dysfunction and cellular stress pathways. Publications highlight collaborations with leading figures like Professor Doug Turnbull and Professor Robert Taylor.