John Shaffer

Dr. John Shaffer is an Assistant Professor at the University of Pittsburgh School of Dental Medicine, specializing in genetic research. His work focuses on applying statistical and bioinformatics methods to understand genetic contributors to complex diseases like orofacial clefts, dental caries, and craniofacial phenotypes. He explores epigenetic mechanisms, gene-environment interactions, and 3D morphological analysis.

Education: PhD in Human Genetics, University of Pittsburgh (2008).

Research interests include:

• Heritability and linkage analysis
• Genetic architecture of craniofacial traits
• Epigenomic studies in cancer and neurotrauma recovery
• Public health disparities in oral care
• Genetic epidemiology of dental diseases

Publications highlight advancements in:

• Cranial vault morphology genetics
• Orofacial cleft risk loci identification
• Genetic basis of dental caries
• Environmental influences on oral health

Collaborations include the GLIDE2 oral health genomics consortium and multi-ethnic GWAS initiatives.