Jianping Li

Dr. Jianping Li is an Assistant Professor in the Department of Pharmacology, Physiology, & Cancer Biology at the College of Life Sciences. He is a physician-scientist specializing in hematology and oncology with over ten years of clinical experience. His laboratory is located at the Bluemle Life Sciences Building (802 BLSB, 233 S. 10th Street, Philadelphia, PA 19107), and he can be contacted at 215-503-2021.

His research integrates epigenetics, cancer biology, and translational therapeutics, with a focus on:

• Epigenetic dysregulation in blood cancers
• Hematopoietic/cancer stem cell dynamics
• T-cell immunity modulation
• Multi-omics approaches (genomics, epigenomics)
• Therapeutic targeting of therapy-resistant malignancies

Key discoveries include elucidating ASXL2's role in myeloid malignancies, defining NSD2 mutation-driven relapse mechanisms in leukemia/lymphoma, and developing novel epigenetic therapies to overcome glucocorticoid resistance. His long-term goal is to translate chromatin regulator insights into effective clinical interventions.