Jennifer Andexer

Prof. Dr. Jennifer Andexer holds the Heisenberg Professorship in Pharmaceutical and Medicinal Chemistry at the University of Freiburg's Institute of Pharmaceutical Sciences. She leads the ANDEXER LAB, focusing on SAM-dependent enzyme systems, biocatalytic methylation, and cofactor regeneration strategies. Her research bridges biochemistry, enzymology, and synthetic biology, with applications in sustainable chemical synthesis and drug design. Key achievements include developing regeneration systems for SAM-dependent reactions and pioneering enzyme engineering for chemoselective alkylation.

• Affiliations: Institute of Pharmaceutical Sciences, University of Freiburg; Spokesperson of DFG Research Group FOR 5596
• Education: PhD in Molecular Enzyme Technology (2008), Postdoc at University of Cambridge (2008-2010)

Research interests span enzymatic cofactor regeneration, methyltransferase mechanisms, and multi-enzyme cascades. Notable grants include ERC Starting Grant (2016) and DFG funding for FOR 5596. She has received awards for both research and teaching excellence, including the Heinz Maier-Leibnitz Award (2018).

Her lab collaborates with institutions like University of Stuttgart (PyEED project) and industry partners. Ongoing projects include biomimetic SAM regeneration and exploring SAM analogues in metabolic pathways. The lab actively mentors students through thesis programs and offers state-of-the-art facilities including HPLC-MS, NMR, and anaerobic chambers.