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Frank L. Brown is a Professor of Chemistry & Biochemistry at the University of California, Santa Barbara, with a joint appointment in Physics and the Biomolecular Sciences & Engineering (BMSE) program. His research focuses on theoretical and computational studies at the interface of physical chemistry and biophysics, particularly biomembrane dynamics and spectroscopy. Dr. Brown received his B.S. in Chemistry and B.A. in Applied Mathematics from UC Berkeley, followed by a Ph.D. in Physical Chemistry from MIT. He has held postdoctoral appointments at UC San Diego and the University of Chicago before joining UCSB in 2001. He is the recipient of prestigious awards including the Alfred P. Sloan Research Fellowship and the Presidential Early Career Award in Science and Engineering. His laboratory employs tools from statistical mechanics, hydrodynamics, and quantum mechanics to study biomembrane structure, dynamics, and interactions with embedded proteins. Key research areas include lipid bilayer fluctuations, membrane protein diffusion, and interpretation of spectroscopic techniques like single-molecule fluorescence and neutron spin echo. Dr. Brown has mentored numerous graduate students and postdoctoral researchers, with notable alumni including Brian Camley, Max Watson, and Golan Bel. His research is supported by grants from agencies such as the National Science Foundation and the Department of Energy. He directs the Brown Research Group, which collaborates with institutions like the CNSI Center for Scientific Computing. His work bridges computational modeling and experimental biophysics, advancing understanding of membrane systems in health and disease.

• Physical Chemistry
• Biophysics
• Biomembranes
• +3 more

Bradley D. Olsen is a full professor in the Department of Chemical Engineering at the Massachusetts Institute of Technology (MIT), where he leads research at the intersection of polymer science, soft matter physics, and bioengineering. His work focuses on designing materials for critical applications in biotechnology, hemostasis, and sustainable polymer development while advancing fundamental understanding of polymer network mechanics and self-assembly. Education: Ph.D. in Chemical Engineering, University of California Berkeley (2007) S.B. in Chemical Engineering, Massachusetts Institute of Technology (2003) Olsen's research spans protein-based materials, block copolymer phase behavior, and mechanochemical hydrogels. He has pioneered methods for quantifying polymer network topology, developing hemostatic nanoparticles, and creating bio-inspired materials for selective biomolecular transport and medical applications. His recent publications emphasize data-driven approaches to polymer characterization and educational outreach in materials science. Scientific Awards: American Physical Society (APS) Fellow (2023) Fulbright Amazonia Scholar (2023) Alexander and I. Michael Kasser Chair in Chemical Engineering (2021) ACS Macro Letters Young Investigator Award (2021) MIT Committed to Caring Honor (2019) AIChE Owens Corning Early Career Award (2019) APS Dillon Medal (2018) Kavli Emerging Leader in Chemistry (2017) ACS Polymer Division Fellow (2016) Camille Dreyfus-Teacher Scholar (2015) Alfred P. Sloan Research Fellow (2014) NSF Career Grant (2013) NIH Postdoctoral Fellowship (2008-2009) Hertz Fellow (2003-2007) Barry M. Goldwater Scholarship (2002) Olsen has received significant grant support including NSF Career (2013) and AFOSR (2012) awards. His teaching activities include innovative international outreach like the 2025 soccer-themed science camp in Brazil. The Olsen Group at MIT explores advanced materials with applications ranging from trauma care to sustainable polymers.

• Polymer Science
• Materials Engineering
• Soft Condensed Matter Physics
• +4 more

Prof. Dr. Ahmet Tutar is a faculty member in the Department of Chemistry at Sakarya University . His academic activities include teaching courses such as Organic Chemistry I/II , Organic Synthesis Design , and Stereochemistry , alongside supervising numerous master's theses in organic synthesis and humic substance applications. Research Interests: Focus on bromination reactions , BODIPY dye synthesis , humic/fulvic acid characterization , computational chemistry , and pharmaceutical applications of organic compounds. Key Article Trends: Recent publications emphasize photobromination methods , metal-organic frameworks , and biological activity of brominated derivatives , with keywords spanning organic synthesis , biochemistry , and environmental chemistry . Thesis Supervision: Guided 35+ master's theses (2007-2013) on topics like synthesis of brominated indan derivatives , humic acid extraction , and photobromination of terpenes .

• Organic Chemistry
• Photochemistry
• Bromination Reactions
• +3 more

Wengong Jin is an Assistant Professor at the Khoury College of Computer Sciences, Northeastern University, and a visiting research scientist at the Eric and Wendy Schmidt Center at the Broad Institute. He holds a PhD from MIT CSAIL, advised by Prof. Regina Barzilay and Prof. Tommi Jaakkola. Research Interests: His work focuses on geometric and generative AI models for drug discovery, biology, and chemical engineering. Key areas include equivariant neural networks (e.g., FAFormer), diffusion models for binding energy prediction, antibody/enzyme design (RefineGNN, SurfPro), and molecular design through graph neural networks (Junction Tree VAE). He also explores domain generalization and systems for autonomous molecular discovery. Publications: His research has been published in top venues like NeurIPS, ICLR, ICML, Nature, Science, and Cell. Recent breakthroughs include discovering novel antibiotics using explainable AI and designing synergistic drug combinations for cancer treatment. Awards: He has received the BroadIgnite Award, Dimitris N. Chorafas Prize, and MIT EECS Outstanding Thesis Award for his contributions to computational biology and AI-driven drug discovery. Teaching: Currently teaches a PhD seminar on AI for Science, focusing on integrating machine learning into scientific discovery processes.

• AI for drug discovery
• Generative AI models
• Geometric deep learning
• +5 more

David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.

• Natural Products Chemistry
• Medicinal Chemistry
• Biosynthesis
• +4 more

John M. Woodley is a distinguished Professor in the Department of Chemical and Biochemical Engineering at the Technical University of Denmark (DTU), where he leads research at the PROSYS - Process and Systems Engineering Centre and contributes to the DTU Microbes Initiative. With over 30 years of experience, he has established himself as a leading expert in biocatalysis and bioprocess engineering, with research spanning both theoretical and experimental work across multiple scales. His primary research interests focus on the interface of bioprocess engineering, process chemistry, and reaction engineering. Dr. Woodley's work encompasses multi-step biocatalysis (including systems biocatalysis and flow chemistry), downstream processing from biocatalytic reactors and fermentations (including ISPR), modeling tools for bioprocess assessment (thermodynamics, kinetics, process simulation, economic evaluation), and bio-oxidations (including oxygen supply methods). His enzymatic investigations particularly target alcohol oxidases, carbohydrate oxidases, cytochrome P450s, Baeyer-Villiger monooxygenases, and transaminases. His research portfolio demonstrates consistent innovation in sustainable chemical production, with particular emphasis on enzymatic synthesis of pharmaceuticals and chemicals from renewable resources. Analysis of his recent publications reveals a strong focus on overcoming industrial implementation challenges, particularly regarding enzyme stability in various reactor environments, optimization of multi-enzyme systems, and scale-up methodologies for biocatalytic processes. Dr. Woodley actively supervises multiple PhD students and leads several significant research projects, including 'P450-based biocatalytic processes for the pharmaceutical industry' (2025-2028), 'Integrated model for up- and downstream bioprocess intensification' (2024-2027), and 'ENFACE: A tool for prediction of enzyme stability at gas-liquid interfaces' (2024-2027). His work has resulted in an impressive publication record of 781 research outputs across various formats, including journal articles, book chapters, and conference proceedings. His research group operates within the Department of Chemical and Biochemical Engineering at DTU, utilizing advanced facilities for biocatalysis research, including specialized reactor systems for studying gas-liquid interfaces, computational modeling resources, and laboratories for enzyme characterization and bioprocess development. Through his leadership in the PROSYS center, he contributes to DTU's strategic focus on sustainable process technologies and systems engineering.

• Biocatalysis
• Bioprocess Engineering
• Enzyme Technology
• +6 more

Dr. Monica E. McCallum is an Assistant Professor of Chemistry in the Department of Chemistry at the University of Pennsylvania’s School of Arts & Sciences. Her research focuses on understanding the biochemical origins of natural products and their roles in microbial communication. She leads the McCallum Lab, which employs interdisciplinary approaches combining organic synthesis, biochemistry, microbiology, and microscopy to study microbial natural products in their native contexts. Education: 2016 – Postdoctoral Fellow at Harvard University under Prof. Emily P. Balskus 2016 – PhD in Organic Chemistry from Baylor University 2013 – PhD Candidate at Colorado State University 2011 – B.S. in Chemistry from University of California, Irvine Research Interests: Dr. McCallum’s work bridges organic synthesis and microbiology to decode microbial metabolite functions. Key themes include: Synthesizing complex natural products and their biosynthetic precursors Discovering novel enzyme-catalyzed reactions Unraveling microbial communication mechanisms via natural products Investigating environmental microbial community dynamics Lab & Collaborations: The McCallum Lab emphasizes interdisciplinary collaboration, integrating techniques from organic chemistry, molecular biology, and microscopy to study natural products in situ. Current projects focus on diazeniumdiolate biosynthesis pathways and enzymatic detoxification of marine toxins.

• Microbial Chemistry
• Natural Products Synthesis
• Biochemistry
• +3 more

Ulf Hanefeld is a Full Professor and Section Leader in the Department of Biotechnology at the Faculty of Applied Sciences , Delft University of Technology (TU Delft) , where he leads the Biocatalysis research section. His work integrates chemistry and biology to develop sustainable synthetic methodologies using enzymes. PhD from Georg-August-Universität zu Göttingen (1993) Postdoctoral experience at Imperial College London, University of Cambridge, and TU Delft Recipient of a Royal Netherlands Academy of Arts and Sciences (KNAW) fellowship His research interests center on biocatalysis , particularly enzymes that enable difficult chemical transformations such as C–C bond formation , enantioselective hydration , and ozonolysis . He focuses on enzyme discovery, engineering, immobilization, and application in flow chemistry to achieve sustainable and efficient synthesis. His work spans from fundamental enzyme mechanism studies to industrial applications in green chemistry . The publication trends reveal a consistent focus on enzyme immobilization , flow reactor systems , and chemo-enzymatic cascades . His recent work emphasizes the use of hydroxynitrile lyases , aldolases , and methyltransferases for the synthesis of chiral intermediates under environmentally benign conditions. The integration of biocatalysis with continuous manufacturing highlights a strong commitment to industrial applicability and process sustainability. Scientific contributions and recognition : Active contributor to high-impact journals in chemistry and biotechnology Coordinated research in the CassaFLOW project (international academic-industrial collaboration) Author of influential reviews, e.g., in Chemical Society Reviews (2022) Teaching and supervision : He teaches Catalysis (Bachelor) and Advanced Biocatalysis (Master), and supervises numerous Master’s theses (MEP) and Bachelor’s projects (BEP) . Students in his group are actively involved in research and often become co-authors on scientific papers. Projects center on green chemistry, enzyme engineering, and spectroscopic analysis of biochemical systems. Laboratory and research environment : The Ulf Hanefeld Group operates within the Biocatalysis section, a multidisciplinary environment fostering collaboration on enzyme discovery, immobilization, and cascade reactions. The group emphasizes practical innovation, with strong links to industry and international research networks.

• Biocatalysis
• Enzyme Engineering
• Green Chemistry
• +7 more

Prof. Dr. Mathias Christmann is a faculty member at the Institute of Chemistry and Biochemistry, Freie Universität Berlin , leading the research group in Organic Chemistry . His work focuses on strategic and methodological challenges in synthetic chemistry, particularly in total synthesis, organocatalysis, and renewable resource transformations. Position: Professor Contact: mathias.christmann@fu-berlin.de Location: Takustr. 3, Room 24.16, 14195 Berlin Research Interests include: Natural product-inspired small molecule synthesis for biological pathway modulation Minimizing C-C bond formations through selective functionalization of terpene building blocks Organocatalytic and metal-catalyzed reactions in multistep sequences Flow chemistry applications for scalable and sustainable synthesis Biological evaluation of TRPC channel agonists/antagonists for cancer therapy Publication Trends highlight expertise in total synthesis of complex terpenoids, organocatalysis for stereocontrolled reactions, flow chemistry for late-stage transformations, and TRPC4/5 channel modulation in renal cancer studies. His group pioneers asymmetric desymmetrization , photo-oxidation protocols , and electrosynthesis methods with minimal reagent waste. Advisees include PhD candidates Jan-Hendrik Dickoff , Mayar Elbendary , Nadine Kreidt , Tobias Olbrisch , Kamar Shakeri , and Zhen Wang , focusing on terpene-based drug discovery and catalytic reaction design.

• Organic Chemistry
• Natural Product Synthesis
• Organocatalysis
• +6 more

Michael Groll serves as Professor and Chair of Biochemistry at the Technical University of Munich (TUM), where he leads structural biology and enzymology research with a focus on proteasome mechanisms and inhibitor development. His laboratory, located at the Ernst-Otto-Fischer-Str. 8 campus in Garching, maintains active collaborations in drug discovery for cancer and infectious diseases. His primary research domains include proteasome inhibition, enzyme catalysis, and natural product biosynthesis, employing X-ray crystallography, biochemical assays, and bioengineering to dissect molecular mechanisms. Recent work emphasizes AI-guided enzyme optimization, bacterial stress response targeting, and structural characterization of halogenation enzymes, reflecting interdisciplinary approaches bridging chemistry and biology. Analysis of his 2023-2025 publications reveals consistent innovation in proteasome-targeted therapeutics, with 15 high-impact papers featuring structural insights into enzyme-inhibitor complexes and biosynthetic pathways. Key trends include engineering megasynthetases for immunoproteasome inhibitors, optical control of protein degradation, and elucidating metal-dependent mechanisms in antibiotic biosynthesis. No scientific awards were documented in the provided source material. While specific grant details and student mentorship records were not disclosed, his extensive publication record indicates leadership in collaborative research projects involving structural biology and chemical biology methodologies. The Chair of Biochemistry under Prof. Groll operates as a hub for structural enzymology, housing facilities for protein crystallography, enzyme kinetics, and natural product characterization. His team actively contributes to TUM's research ecosystem through partnerships with pharmaceutical groups and international structural biology consortia.

• Proteasome Research
• Structural Biology
• Enzyme Mechanisms
• +2 more

Prof. Johannes A. Lercher is a retired professor (as of April 2023) at the Technical University of Munich (TUM), holding the Chair of Chemical Technology II within the Department of Chemistry. His research focuses on heterogeneous catalysis, particularly understanding catalytic processes at solid-liquid and solid-gas interfaces, with applications in sustainable energy production, CO₂ conversion, and catalytic upcycling of polymers. He has held academic positions at the University of Twente (Netherlands) and the Pacific Northwest National Laboratory (USA), and has been Editor-in-Chief of the Journal of Catalysis . His honors include the Alwin Mittasch Prize (2021), ENI Award (2016), and Kozo Tanabe Prize (2013). His recent work emphasizes low-temperature polymer upcycling, methane activation, and bioinspired catalyst design, leveraging advanced spectroscopic and operando techniques. Despite retirement, his contributions to catalysis research remain impactful. Education: PhD (1980) and Habilitation (1985), Vienna University of Technology Visiting Lecturer, Yale University (1982) Research Interests: Heterogeneous catalysis, catalytic interfaces, sustainable energy carriers, CO₂ valorization, and polymer waste upcycling. Key areas include: Design of catalysts for selective hydrocarbon synthesis Mechanistic studies using advanced spectroscopy Development of scalable catalytic processes for industrial applications Recent Trends in Publications: Focus on low-temperature polymer recycling (e.g., PVC and polyolefin upcycling), methane activation via novel catalysts (e.g., Co 2+ in ZSM-5), and bioinspired catalytic strategies. His work bridges fundamental catalysis with industrial relevance, emphasizing sustainability and energy efficiency. Awards and Recognition: Member, Academia Europaea and US National Academy of Engineering Recipient of multiple international catalysis awards (see full list above) Grants and Labs: Led the Institute for Integrated Catalysis (Pacific Northwest National Lab, 2011–present). His research groups have pioneered studies on zeolite-confined reactions and interfacial catalysis, with collaborations spanning academia and industry. Labs/Teams: Active in the TUM Department of Chemistry and international networks focused on catalytic innovation for a carbon-neutral economy.

• Catalysis
• Sustainable Energy
• Chemical Engineering
• +3 more

Associate Professor LI Zhi leads the Chemical & Biomolecular Engineering Department at the National University of Singapore (NUS). His research focuses on advanced biocatalysis for sustainable manufacturing, bio-based fuels, and functional materials. He holds a PhD in Organic Chemistry from the University of Vienna (1991), an MEng from Chinese Academy of Forestry (1985), and a BSc from Nanjing University (1982). Institutional Affiliations: NUS Faculty of Engineering, NUS ChBE Department. His lab actively collaborates with global institutions like A*STAR and the Singapore Catalysis Society. Research highlights include enzyme engineering for cascade reactions, CO₂ utilization, and biomaterial synthesis. Research Interests: Discovery of novel biocatalysts, engineering of biocatalytic systems, renewable feedstock utilization, and smart material development. Recent work emphasizes cascade biotransformations for chiral chemicals and sustainable processes. Lab Activities: Hosted international conferences (e.g., Southeast Asia Catalysis Conference 2019), collaborations with industry leaders (GSK, Pfizer), and visits from distinguished researchers like Prof. Zhao Huimin. Student milestones include PhD completions (e.g., Wang Wen, Joel Choo Ping Syong) and postdoc contributions across institutions. Grants & Labs: Active in grants related to biocatalysis and green chemistry. Lab members include researchers like Dr. Nicholas Goh and PhD students Li Li. Infrastructure includes advanced facilities for biotransformations and material synthesis.

• Biocatalysis
• Green Chemistry
• Sustainable Manufacturing
• +4 more

Amy E. Fraley is an Assistant Professor at ETH Zürich, Department of Chemistry and Applied Biosciences, and leads the Medicinal Chemistry Research Group. Her cross-disciplinary work bridges natural products biosynthesis, pharmaceutical sciences, and environmental sustainability through enzymatic chemistry and biotechnology. BSc in Chemistry, Millersville University of Pennsylvania (2014) PhD in Medicinal Chemistry, University of Michigan College of Pharmacy (2019) Postdoctoral work at ETH Zürich Institute of Microbiology under Prof. Jörn Piel Her research focuses on harnessing biosynthetic enzymes (e.g., halogenases, monooxygenases, Diels-Alderases) to create sustainable bioactive metabolites. She explores natural product biosynthesis in fungi and marine bacteria, targeting disease mechanisms and green chemistry applications. Recent work includes metagenomic studies of Lake Chilika microbial mats and polyketide synthase engineering. Notable scientific awards include the 2024 JSP Fellow at Bürgenstock Conference, 2018 Rackham Predoctoral Fellowship, and multiple University of Michigan honors. Her group secured funding from the ETH4D Doctoral Mentorship Grant and Messerli Foundation . Collaborations span structural biology, synthetic chemistry, and microbiology, with key contributions to flavoenzyme characterization and bioactive compound libraries . The lab emphasizes interdisciplinary training and innovation in biocatalytic tools for organic synthesis.

• Natural Products Biosynthesis
• Biotechnology
• Biochemistry
• +6 more

Professor Klavs F. Jensen is the Warren K. Lewis Professor of Chemical Engineering and Professor of Materials Science and Engineering at MIT. His research focuses on integrating automation, machine learning, and robotics to accelerate materials discovery and pharmaceutical synthesis. He leads the Jensen Research Group, pioneering automated reaction systems with online analytics and optimization algorithms. Education: MS in Chemical Engineering (Technical University of Denmark, 1976); PhD in Chemical Engineering (University of Wisconsin, 1980). Research Interests: Thermochemistry, electrochemistry, photochemistry, Bayesian optimization, high-throughput experimentation, and AI-driven synthesis planning. He collaborates with MIT’s Machine Learning for Pharmaceutical Discovery Consortium to develop algorithms for drug development and process chemistry. Awards: Member of National Academy of Sciences (2017), Member of National Academy of Engineering (2002), Fellow of the American Association for the Advancement of Science (2007), and Fellow of the National Academy of Inventors (2022). Grants & Labs: Editor-in-Chief of Reaction Chemistry and Engineering ; holds 63 US patents and over 490 journal articles. His lab’s innovations include ASKCOS (open-source synthesis planning software) and automated platforms for closed-loop molecular discovery.

• Materials Science
• Chemical Engineering
• Machine Learning
• +4 more

Professor George Britovsek (FRSC) is a leading figure in catalysis and sustainable carbon management at Imperial College London . As Director of the MRes in Catalysis & Engineering and Head of Teaching in Inorganic Chemistry, he bridges academic leadership with cutting-edge research. His work focuses on transition metal complexes for converting ethylene , alkanes , biomass , and CO₂ into valuable chemicals and fuels through industrial collaborations. Education : M.Sc. (Technical University of Aachen, 1990), Ph.D. (Aachen, 1993) under Prof. W. Keim Postdoctoral Training : University of Tasmania (1994-1996), Imperial College London (1996-2000) His research interests span: Selective oxidation of alkanes using bio-inspired iron complexes Alkene conversions to functional polymers via novel catalysts CO₂ valorization into polymers and cyclic carbonates Biomass-derived feedstocks for chemical synthesis Recent catalysis trends highlight his work on: Designing Fe-N/C catalysts for epoxidation Developing PN3P pincer ligands for H₂ activation Creating degradable polyethylene via iron-catalyzed chain growth Modeling alternating α-olefin distributions in chromium systems Awards : Fellow of the Royal Society of Chemistry (FRSC) Students & Collaborators actively engage in: Photocatalytic polymer degradation Electrocatalytic CO₂ conversion Functionalized polymeric materials 3D-printed catalytic scaffolds His Britovsek Research Group operates at the Molecular Sciences Research Hub, White City Campus, advancing both homogeneous and heterogeneous catalysis through experimental and computational approaches.

• Catalysis
• Sustainable Carbon Management
• Transition Metal Complexes
• +3 more