Jason Gleghorn

Jason Gleghorn is an Associate Professor in the Department of Biomedical Engineering at the University of Delaware, affiliated with the Ammon Pinizzotto Biopharmaceutical Innovation Center. His research focuses on understanding how cells assemble into functional tissues through microfluidic and microfabrication technologies. He holds a Ph.D. in Biomedical Engineering from Cornell University and postdoctoral fellowships at Princeton and Cornell Universities. His work integrates engineering, molecular biology, and materials science to study biophysical and chemical signals driving tissue development and disease. Key research areas include microfluidics, regenerative medicine, and organ-on-chip systems.

Education:

• Ph.D. in Biomedical Engineering, Cornell University
• B.S. in Mechanical Engineering, Worcester Polytechnic Institute (WPI)
• Postdoctoral Fellowships:
  • Princeton University (Chemical & Biological Engineering)
  • Cornell University (Mechanical & Aerospace Engineering)

Research Interests: The Gleghorn Lab develops technologies to study cellular communication in developing organs and engineered tissues. Key projects involve:

• Microfluidic platforms for lung development modeling
• Quantitative analysis of tissue morphogenesis
• 3D organotypic culture systems
• Biomechanical regulation of cell behavior
• Therapeutic approaches for regenerative medicine

Publications & Trends: Recent work emphasizes organ-on-chip systems, placental transport modeling, and mechanistic studies of congenital defects like congenital diaphragmatic hernia. His articles bridge engineering innovations with clinical relevance, focusing on lung mechanics, vascular biology, and nanotechnology-based delivery systems.

Labs & Teams: The lab collaborates across disciplines to engineer physiologically relevant tissue models. The Glehorn Lab actively seeks students and researchers interested in engineering-biology interfaces.