James Platts

Dr. James Platts is a Professor of Computational and Physical Chemistry at Cardiff University's School of Chemistry. His research leverages theoretical and computational methods to investigate non-covalent interactions, metal-biomolecule binding, and chemical reactivity, with applications in neurodegeneration, drug design, and materials science.

Prof. Platts' work focuses on molecular dynamics simulations of amyloid-β and α-synuclein to elucidate metal-induced structural changes, quantum chemical studies of inorganic complexes, and predictive modeling of pharmaceutical compounds. His group employs density functional theory (DFT), molecular dynamics (MD), and spectroscopic validation to explore fundamental chemical processes.

Recent publications highlight trends in biomolecular simulations (e.g., pH/metal effects on peptides), luminescent metal complexes, and uranyl binding mechanisms. Interdisciplinary collaboration is evident in studies combining experimental synthesis with computational insights.