About
David Eisenberg is a Professor at the University of California, Los Angeles, specializing in structural biology and neurodegenerative diseases. His research focuses on amyloid proteins, including tau, α-synuclein, and TDP-43, using cryo-EM and computational methods to understand aggregation mechanisms in Alzheimer's and related disorders.
- Key Research Areas: Amyloid formation, cross-β spine structures, structure-based inhibitor design
- Recent Trends: Development of D-peptide inhibitors for tau, liganded nanoparticles for α-synuclein imaging
- Collaborations: Extensive work with UCLA's MBI (Molecular Biology Institute) and international amyloid research groups
His scientific contributions include defining the structural basis of amyloid polymorphism and identifying critical pathways for protein aggregation, with applications in both neurodegenerative disease therapy and materials science. Awards and honors are not explicitly listed in the provided text, but his work has been published in top-tier journals like Nature, Science, and PNAS.
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