Jacob Reimer

Jacob Reimer is an Assistant Professor in the Department of Neuroscience at Baylor College of Medicine. His research focuses on understanding brain states and multimodal integration across corticothalamic circuits, particularly how attention shifts and sensory processing change dynamically without anatomical rewiring. He employs advanced techniques including in vivo whole-cell patching, multiphoton calcium imaging, optogenetics, and viral tracing methods. Reimer earned his PhD in Neuroscience from the University of Chicago (2009) and leads the Reimer Lab, which explores brain state fluctuations and functional connectomics in mice.

• Education: PhD in Neuroscience, University of Chicago (2009)
• Laboratory Focus: Cortical circuits, brain state dynamics, sensory integration
• Techniques: Multiphoton imaging, optogenetics, connectomic analysis
• Key Projects: MICrONS collaboration for mouse visual cortex connectomics

His research highlights how pupil size fluctuations correlate with internal brain states and demonstrates the role of acetylcholine dynamics in modulating cortical activity. The lab has pioneered methods for dense neural activity mapping and automated connectomic analysis using tools like NEURD. Collaborations with institutions like Princeton University advance large-scale functional connectomics efforts.

Advising includes mentoring graduate students (e.g., MARIO A GALDAMEZ, Noura Z Hakam) and postdoctoral researchers (e.g., Erin Neyhart, Cameron Lewis Smith). The lab's work bridges experimental neuroscience with computational modeling, contributing to both basic science and translational insights into neural circuitry.