Isabelle Lucet

Isabelle Lucet is an Adjunct Senior Lecturer in the Department of Biochemistry & Molecular Biology at Monash University, within the Faculty of Medicine, Nursing and Health Sciences. Her research focuses on structural biology, drug design, and molecular mechanisms of cellular processes relevant to cancer, plant immunity, and microbial pathogenesis. She has been a Primary Chief Investigator on an NHMRC-funded project (2004–2007) studying JAK/ABL kinases for drug design applications.

Her expertise aligns with UN Sustainable Development Goals, particularly in advancing health and well-being through biomedical research. Key research areas include cancer cell invasion dynamics, plant immune receptor activation, and structural studies of bacterial and viral proteins. Notable projects involve collaborations on EphB6-ephrinB1 signaling in cancer metastasis, ZAR1 immune receptor function in plants, and viral kinase regulation mechanisms.

Recent publications highlight her interdisciplinary work in structural biology, proteomics, and pathogen-host interactions. She has contributed over 58 peer-reviewed articles across diverse topics such as neuroprotection mechanisms, mycobacterial cell wall synthesis, and alphavirus replication strategies.