Harris R Perlman

Harris R Perlman is Chief of Rheumatology in the Department of Medicine at Northwestern University Feinberg School of Medicine and holds the Mabel Greene Myers Professor of Medicine. His research focuses on macrophage biology, inflammatory arthritis, and fibrotic diseases like systemic sclerosis and pulmonary fibrosis.

• Affiliation: Northwestern University
• Academic Rank: Professor
• Key Institutes: Center for Human Immunobiology, NUCATS, Lurie Cancer Center

Research Interests:
His work explores:

• Macrophage heterogeneity in arthritis and fibrosis
• Complement pathway activation in rheumatoid arthritis
• Profibrotic monocyte-derived macrophages in lung disease
• Role of Wnt-beta catenin in macrophage pathogenesis
• Transcriptional profiling for precision medicine in autoimmune diseases
• Age-related immune dysregulation in inflammatory conditions

Scientific Awards:

• Mentor of the Year (2022)

Clinical Trials:

• Synovial Macrophage Transcriptional Signatures for Predicting Therapeutic Efficacy
• Pathogenic Wnt-beta catenin target genes in macrophages and fibrosis