Hans Bouwmeester

Hans Bouwmeester is a Full Professor in Toxicology at Wageningen University & Research, specializing in chemical risk assessment, nanomaterial toxicity, and in vitro modeling. His work focuses on integrating artificial intelligence and physiologically based kinetic (PBK) models to predict toxic effects of contaminants like organophosphate pesticides, microplastics, and mycotoxins. He leads projects exploring the health impacts of foodborne contaminants in inflammatory bowel disease and developing animal-free testing methods. Key collaborations include EU initiatives like the ONTOX project and the GUTTEST program, which utilize advanced in vitro models such as gut-on-a-chip systems.

Research interests span toxicokinetics, nanoplastics exposure, and the application of Bayesian networks for nanomaterial hazard ranking. His team addresses translational challenges in linking in vitro data to in vivo outcomes, with a focus on bile acid metabolism and cardiotoxicity prediction. Bouwmeester has supervised over 10 PhD candidates, including studies on microplastic hazard assessment, nanomaterial gastrointestinal fate, and AI-driven data extraction for risk assessment.

Notable contributions include datasets on nanoplastics' protein corona effects and transcriptomic analyses of intestinal cell responses. His work is published in journals like Ecotoxicology and Environmental Safety, Toxicology, and Environmental Science & Technology, emphasizing open-access research and interdisciplinary approaches to chemical safety.