Germana Meroni

Germana Meroni is an Associate Professor of Genetics at the University of Trieste, leading research on the TRIM family of E3 ubiquitin ligases in genetic diseases. Her work spans molecular genetics, biomedicine, and neurodevelopmental disorders.

• Biomedical Research Group: Ubiquitination in genetic diseases
• Doctoral Studies Coordinator: Cycles XXXII-XXXVIII in Molecular Biomedicine
• Research Projects: MID1 membraneless organelles, TRIM32 pathologies, and ubiquitination mechanisms

Her research focuses on TRIM proteins' roles in ubiquitination, particularly in Opitz Syndrome (MID1/TRIM18) and Limb-Girdle Muscular Dystrophy (TRIM32). She investigates E3 ligase specificity, substrate interactions, and cytoskeletal regulation through extensive patient screening and mouse models.

Recent studies highlight ubiquitination's impact on neuronal homeostasis, microtubule dynamics, and disease-specific substrates. Her publications cover genetic syndromes, enzyme kinetics, and protein localization mechanisms.

Current group members include post-doctoral fellows and PhD students working on muscle differentiation, cerebellar development, and ubiquitin chain topology. Former students hold positions at institutions like TIGEM, Novartis, and EMBL.