About
Dr. Ellen Tisdale is Associate Professor in the Department of Pharmacology at Wayne State University School of Medicine. Her laboratory investigates molecular mechanisms of membrane transport with focus on Rab2 protein function.
Research examines retrograde transport regulation from vesicular tubular clusters to the endoplasmic reticulum, with implications for cancer and neurodegenerative diseases. Utilizes molecular biology, microscopy, and biochemical approaches to characterize trafficking machinery.
Key findings include Rab2's role in vesicle formation through interactions with Src, aPKCi, and GAPDH. Published in Journal of Biological Chemistry and other leading journals.
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