About
Yu Wu is a Visiting Research Scientist in the Department of Pharmacology at Yale University's School of Medicine. His research focuses on cellular membrane dynamics, synaptic vesicle function, and neurodegenerative diseases such as Parkinson's. He investigates lipid transport proteins, endocytic pathways, and autophagosome biogenesis, with a particular interest in molecular mechanisms underlying synaptic pathology and cellular dysfunction.
- Research Interests: Synaptic vesicle biogenesis, lipid metabolism, ER-membrane contact sites, Parkinson's disease protein interactions, and autophagy regulation.
- Techniques: Electron microscopy, immunohistochemistry, iPSC-derived neuron modeling, and proximity proteomics.
Dr. Wu's work bridges cell biology and neuroscience, with recent studies exploring how mutations in endocytic proteins impact dopaminergic neurons and how lipid transport proteins regulate membrane homeostasis. His articles highlight interdisciplinary approaches to understanding fundamental cellular processes and their roles in disease.
His research trends emphasize molecular mechanisms of membrane trafficking, particularly in contexts like synaptic dysfunction and neurodegeneration. Collaborative studies with other labs focus on translating cellular findings into disease models.
