Douglas Cyr

Douglas Cyr, PhD, is a Professor in the Department of Cell Biology and Physiology at the UNC School of Medicine, University of North Carolina at Chapel Hill. His research focuses on protein folding mechanisms, proteotoxic stress responses, and cellular quality control pathways. He holds primary faculty appointments in the CBP Curriculum and CSIP T32 Training programs.

Education:

• Bachelor of Science (BS), Roger Williams University, 1984
• Doctor of Philosophy (PhD), University of Rhode Island, 1989
• Postdoctoral Training, University of North Carolina at Chapel Hill, 1993
• Postdoctoral Training, University of Munich, 1995

Research Interests: The Cyr laboratory investigates Hsp70 chaperone systems and their role in protein triage, ER-associated degradation (ERAD), and autophagy. Key projects include studying CFTR misfolding in cystic fibrosis, ER quality control mechanisms, and the translational implications of chaperone dysfunction in cancer and genetic disorders. Research combines biochemical, cell biological, and genetic approaches.

Publications: No specific articles listed in provided text.

Awards: No awards explicitly mentioned in current data.

Lab Resources: Located in 4312B MBRB, Chapel Hill. Lab focuses on molecular chaperone networks and stress response pathways with translational medicine applications.