David Stoltz

David Stoltz, MD, PhD, is a Professor at the University of Iowa, with appointments in the Department of Internal Medicine - Division of Pulmonary, Critical Care and Occupational Medicine, Biomedical Engineering, and Molecular Physiology and Biophysics. He serves as Director of both the Division of Pulmonary, Critical Care and Occupational Medicine and the Physician Scientist Training Pathway at the Carver College of Medicine.

His research focuses on the pathogenesis of cystic fibrosis, particularly in airway epithelial and smooth muscle cells, the role of paraoxonases in Pseudomonas aeruginosa quorum-sensing, mucociliary clearance, and advanced airway imaging. He utilizes porcine models to study early disease mechanisms and potential therapies.

The recent publications highlight a strong focus on translational cystic fibrosis research, including gene therapy, CFTR modulation, airway inflammation, mucus structure, and neural control of airways. These studies employ cutting-edge techniques such as transcriptomics, advanced imaging, and porcine disease models, reflecting a multidisciplinary approach bridging molecular biology, physiology, and clinical medicine.

Dr. Stoltz is affiliated with several major research centers, including the Cystic Fibrosis Research Center, Cardiovascular Research Center, Fraternal Order of Eagles Diabetes Research Center, and the Iowa Institute for Biomedical Imaging. He is actively involved in training physician-scientists and leads a productive research laboratory. His work is supported by significant NIH and foundation funding, though specific grants are not listed.