David Hill
Research Professor · Respiratory Medicine
University of North Carolina at Chapel HillAbout
David Hill is a Research Professor at the University of North Carolina at Chapel Hill, specializing in respiratory mucus biology and cystic fibrosis. His research focuses on mucus rheology, microbial biofilms, and mucociliary clearance mechanisms. He explores how genetic and environmental factors influence airway mucus properties in diseases like cystic fibrosis and hyper-IgE syndrome.
His work spans biophysical characterization of mucus, development of inhalable drug delivery systems, and novel diagnostic tools like ultrasound contrast agents for mucociliary clearance measurement. Key themes include understanding pathological mucus hyperconcentration, DNA-mucus interactions in biofilm formation, and the impact of pollutants on airway defense.
Publications highlight advancements in mucus mechanics, therapeutic strategies for biofilm eradication, and genetic deficiencies affecting nasal polyps and bronchiectasis. His interdisciplinary approach integrates materials science, biophysics, and clinical insights to address muco-obstructive diseases.
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