
About
Christopher J. Shoemaker is Assistant Professor of Biochemistry and Cell Biology at Dartmouth's Geisel School of Medicine, leading research on autophagy mechanisms. His laboratory investigates how cells eliminate toxic structures through degradation pathways, with implications for neurodegeneration, cancer, and aging. Current projects examine selective autophagy targeting, non-canonical degradation routes, and biochemical reconstitution of autophagy machinery.
Shoemaker's work combines cellular and biochemical approaches to study autophagy at molecular resolution. Recent publications focus on receptor-mediated autophagy initiation, ER-phagy mechanisms during nutrient stress, and mitophagy regulation. His team utilizes CRISPR screening to identify novel autophagy factors and employs biochemical reconstitution to define fundamental mechanisms.
Laboratory members include graduate students Brian North, Sam Liu, Carter Tracy, and Adwaita Bose. The lab operates within Dartmouth's Vail Building and maintains collaborative relationships internationally. No specific grants or scientific awards are detailed in the source materials.
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