
About
Bryan Heit is Associate Professor at Western University's Schulich School of Medicine, investigating macrophage function in health and disease. His laboratory focuses on efferocytosis mechanisms and failures in disease contexts.
Research expertise includes phagocyte biology, efferocytosis regulation, antigen processing, and inflammatory disease mechanisms. Applications span atherosclerosis, pneumonia, and autoimmune conditions.
Recent publications describe quantitative methods for efferocytosis measurement, SARS-CoV-2 immune evasion strategies, and synovial macrophage dysfunction in osteoarthritis. Emerging techniques include long-term live cell imaging and fluorescent biosensors.
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Supervises graduate students in microbiology and immunology programs. Research funded by Canadian institutes including studies on efferocytosis impairment in arthritis.
Leads the Heit Lab (www.phagocytes.ca) developing advanced microscopy techniques to study macrophage behavior in real-time during infection and inflammation.
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