Bruce Posner

Bruce Posner is an Associate Professor in the Biochemistry Department at the University of Texas Southwestern Medical Center, where he also serves as Director of the High Throughput Screening Core Facility. His academic journey includes:

• B.S. in Chemistry (honors) from University of Chicago
• Ph.D. in Biological Chemistry from Penn State University
• NIH postdoctoral fellowship at UT Southwestern Medical Center

His research focuses on translating biological insights into preclinical drug discovery programs, with emphasis on:

• High-throughput screening platforms
• Small molecule therapeutic development
• Target identification for cancer and metabolic diseases
• Mechanistic studies of enzyme function and signaling pathways

His recent publications demonstrate strong focus on cancer therapeutics, with consistent themes in:

• Targeted inhibition of metabolic enzymes in tumors
• Nuclear transport mechanisms in disease
• High-throughput screening methodologies
• Personalized medicine approaches for solid tumors

As core facility director, he oversees infrastructure supporting drug discovery projects across UT Southwestern and collaborates extensively with principal investigators.