Brian Feldman

Dr. Brian Feldman is a Professor of Pediatrics (Endocrinology) and Section Chief of Pediatric Endocrinology & Diabetes at Yale School of Medicine, Yale University. He holds the Walter L. Miller Endowed Chair and Distinguished Professorship in Pediatric Endocrinology. Dr. Feldman received his combined MD and PhD from Stanford University, completed residency at Harvard University/Children's Hospital Boston, and fellowship training at UCSF. His research program investigates molecular mechanisms of adipose tissue development and metabolism.

Research Focus: Dr. Feldman's work examines steroid hormone signaling pathways regulating cell fate decisions, particularly glucocorticoid-mediated circadian control of metabolism and brown adipose tissue development. His laboratory studies:

• Adipocyte precursor populations and differentiation mechanisms
• KLF15 transcription factor networks in adipose maintenance
• Glucocorticoid receptor dynamics in metabolic disorders
• Autoregulatory pathways in adipose tissue development

His 15 most recent publications demonstrate consistent focus on adipose biology, with methodologies spanning lineage tracing, metabolic profiling, molecular imaging, and preclinical models. Research trends include:

• Characterization of adipose progenitor populations (2023)
• Circadian regulation of adipogenesis (2017-2018)
• Novel diagnostic platforms (2019)
• Therapeutic targeting of glucocorticoid pathways (2020)

Honors and Awards:

• Walter L. Miller Endowed Chair (UCSF)
• NIH Director's New Innovator Award
• Elected to American Association for Clinical Investigation
• Young Investigator Award (Society for Pediatric Research)
• Clinical Scholars Award (Pediatric Endocrine Society)
• Early Investigator Award (Endocrine Society)

Dr. Feldman has mentored numerous trainees and received recognition for fostering physician-scientist careers. He leads research teams investigating adipose tissue biology and endocrine disorders.