Brian D. Athey

Brian D. Athey is a Professor of Computational Medicine and Bioinformatics and Psychiatry at the University of Michigan Medical School. He serves as Michael Savageau Collegiate Professor & Chair of his department, leading interdisciplinary research in pharmacogenomics, epigenomics, and machine learning applications. His work bridges biomedical informatics with clinical insights in mental health, neurology, and drug response mechanisms.

• Ph.D., Biophysics, University of Michigan (1990)
• B.S., University of Michigan-Dearborn (1982)

Dr. Athey’s research focuses on the pharmacoepigenome, high-throughput 4D imaging, and AI-driven pharmacogenomic pipelines. His lab develops tools for patient-specific drug response prediction, chromatin structure analysis, and next-generation sequencing assays. Collaborations span institutions like Assurex Health, tranSMART Foundation, and Johns Hopkins Medical School.

His publications highlight innovations in pharmacogenomics, including AI integration for variant identification, 4D nucleome modeling, and adverse event ontologies. Recent projects address bipolar disorder treatment personalization, hypertension management, and generative AI workflows to enhance academic productivity.

Scientific Awards:

• NIH Postdoctoral Fellowship 1990-1991
• NIH Postdoctoral Fellowship 1991-1993

Advisees & Collaborations: His lab mentors PhD and Masters students in bioinformatics and biostatistics, with graduates like Ari Allyn-Feuer (GSK AI Products Director) and Alex Kalinin (Broad Institute). Collaborations include NIH-funded initiatives (O’Brien Kidney Core Center, VIOLIN 2.0) and industry partnerships.