Bree Aldridge

Bree Aldridge is a Professor at Tufts University with joint appointments in the School of Medicine (Molecular Biology and Microbiology) and School of Engineering (Biomedical Engineering). Her work bridges cell biology, computational modeling, and antibiotic discovery to combat tuberculosis and drug-resistant pathogens.

Her research focuses on

• Characterizing single-cell determinants of mycobacterial drug tolerance
• Understanding growth heterogeneity control in bacteria
• Engineering optimized antibiotic combination therapies

using quantitative measurements and systems approaches.

Her recent publications highlight trends in multi-drug interaction analysis, single-cell imaging of tuberculosis, and AI-driven antibiotic discovery. She has received multiple teaching honors, including three Best Course nominations from Tufts University.

Grants from the Bill & Melinda Gates Foundation and National Institutes of Health support her work on tuberculosis drug regimen optimization, myeloid cell suppression in granulomas, and stress response modeling. She actively contributes to conferences, symposia, and university committees in systems pharmacology and biosafety.