Axel Sandvig

Dr. Axel Sandvig is an Adjunct Associate Professor at the Department of Community Medicine and Rehabilitation, Umeå University, with a focus on neurodegenerative diseases and neural network engineering. He also serves as a physician at the Department of Clinical Sciences, Umeå University, specializing in neurosciences. His work intersects clinical practice with cutting-edge research in neuroengineering and neurodegeneration.

• Adjunct Associate Professor, Department of Community Medicine and Rehabilitation, Umeå University
• Physician, Department of Clinical Sciences, Umeå University

Dr. Sandvig’s research spans multiple domains of neuroscience, neuroengineering, and biomedical applications. He investigates Alzheimer’s disease using engineered human neural networks with mutations like LRRK2 G2019S and P301L tau, analyzing structural, functional, and connectomic changes. His work also explores neuroplasticity in stroke recovery, nanotechnology for neuroimaging, and lab-on-chip platforms for neuromodulation. Recent studies highlight synaptic connectivity and autophagy pathways as therapeutic targets.

The 15 most recent publications reveal a trend toward neurodegenerative disease modeling, neural network dynamics, and biomedical nanotechnology. Key subfields include LRRK2/tau mutations, small-world network topology, neuroregeneration after ischemia, and gold nanostructure design. His work often involves in vitro models, neuroimaging, and stem cell applications.

Dr. Sandvig collaborates extensively on neuroregenerative therapies, including nanoparticle delivery systems and manganese-enhanced MRI for axonal tracing. His affiliations bridge clinical practice at Norrland University Hospital with academic research at Umeå University.