About
Anindita Basu is an Associate Professor at the University of Chicago, jointly affiliated with the Department of Medicine-Genetic Medicine and the Center for Nanoscale Systems at Argonne National Laboratory. Her interdisciplinary research integrates physics, genomics, molecular biology, and materials science to study biological systems at single-cell resolution with high throughput.
- Institution: University of Chicago
- Department: Medicine-Genetic Medicine
- Academic Rank: Associate Professor
- Joint Affiliation: Center for Nanoscale Systems (Argonne National Lab)
Research focuses on:
- Single-cell epigenomic and transcriptomic profiling of mammalian/microbial cells
- Microfluidic device development for high-throughput biological analysis
- Inter-cellular interaction mapping in disease contexts
- Systems-level organization in complex tissues
Recent publications (2024-2025) emphasize:
- Crohn's disease pathogenesis through chromatin accessibility mapping
- Host-pathogen interactions in inflammatory bowel disease
- Vein geometry hemodynamics in dialysis patients
- Microbial transcriptomic responses to nanostructured surfaces
- Menopausal fallopian tube cellular transformations
Technological innovations include:
- Microfluidic platforms for microbial cell lysis
- mDrop-Seq for yeast/Candida single-cell RNA-seq
- Fixed-cell RNA-seq methodologies
- Droplet-based nucleic acid analysis systems
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