Andrew Adey

Andrew Adey serves as Associate Professor with Tenure in the Department of Molecular and Medical Genetics at Oregon Health and Science University School of Medicine. He leads the Adey Lab and holds memberships in the Knight Cancer Institute, Cancer Early Detection Advanced Research center, and Knight Cardiovascular Institute.

His research focuses on developing single-cell technologies for epigenetic profiling, particularly chromatin accessibility analysis. The Adey Lab specializes in combinatorial indexing strategies that enhance library quality, increase cell throughput, incorporate spatial information, and reduce costs in single-cell experiments. These methodologies are applied to critical areas including neurodevelopment and cancer biology.

Dr. Adey pioneered transposase-based methods for rapid DNA sequencing library construction and extended these techniques to genome-wide DNA methylation analysis. His work produced the first haplotype-resolved genome and epigenome of the HeLa cell line, investigating how genetic variation influences epigenetic regulation.

• 2018 American Society of Human Genetics Early Career Award

Beginning his career at the University of Texas, Dr. Adey researched microarray applications and served as interim director of the UT microarray core facility. He helped establish the UT genome sequencing facility during early next-generation sequencing development. He completed his doctoral work at the University of Washington in Jay Shendure's lab within the Genome Sciences Department.

The Adey Lab continues advancing single-cell genomic technologies, developing innovative approaches that enable comprehensive analysis of epigenetic landscapes in complex biological systems.