
About
Anders Tengholm is a Professor at the Department of Medical Cell Biology, Uppsala University, Faculty of Medicine. His research focuses on molecular mechanisms of hormone secretion in pancreatic islets, particularly insulin and glucagon regulation via cAMP and calcium signaling. He leads a research group investigating diabetic pathophysiology and potential regenerative therapies.
- Current affiliation: Department of Medical Cell Biology, Uppsala University
- Academic rank: Professor
- Contact: Anders.Tengholm@mcb.uu.se
Research interests include:
- CAMP signaling: Oscillatory cAMP dynamics in beta cells, its role in glucose-stimulated insulin secretion, and interactions with calcium signaling
- Islet cell communication: Paracrine regulation in diabetic states, including somatostatin and glucagon secretion defects
- Regenerative approaches: Beta cell regeneration mechanisms and lipid/protein signaling in islet function
His recent publications highlight advancements in understanding type 2 diabetes pathogenesis, islet signaling microdomains, and novel tools for live-cell imaging. Collaborations span molecular biology, diabetes research, and translational medicine, with frequent contributions to high-impact journals like Acta Physiologica, Nature Chemical Biology, and Cell Reports. No listed scientific awards or part-time appointments.
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