About
Amjad Javed is a Professor and Associate Dean at the University of Alabama at Birmingham, with primary appointments in the School of Dentistry - Oral & Maxillofacial Surgery and joint affiliations in Cell, Developmental and Integrative Biology, Otolaryngology, and Biomedical Engineering. His research spans bone biology, cartilage development, and myeloma bone disease.
- PhD in Physiology (University of the Punjab, 2003)
- MS in Zoology/Animal Biology (University of the Punjab, 1992)
Research Interests focus on transcriptional regulation via RUNX2 and Sp7 in skeletogenesis, vascular calcification mechanisms, epigenetic control of bone formation, and tumor-bone microenvironment interactions in multiple myeloma. Key subfields include endochondral ossification, osteoclast differentiation, and nanomatrix-based tissue engineering.
Scientific Contributions include discoveries about RUNX2's role in postnatal bone resorption, λ5 protein's impact on skeletal aging, and heparanase's promotion of myeloma metastasis. His work demonstrates RUNX2's dual function in chondrocyte apoptosis and cartilage degradation.
Teaching & Mentorship involves graduate committee service for over 15 students and instruction in courses like Connective Tissue and Bone, Oral & Skeletal Biology, and Journal Clubs. Collaborations span Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center, Integrative Center for Aging Research, and Biomatrix Eng Regen Med Center.
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