Alok Joglekar

Alok Joglekar, Ph.D., is an Assistant Professor at the University of Pittsburgh with joint appointments in the Department of Computational and Systems Biology and Department of Immunology. His research focuses on systems immunology approaches to T cell antigen discovery, computational modeling of T cell receptor (TCR) interactions, and engineering immune responses for autoimmune and cancer therapies.

Key research areas include:

• Decoding TCR-peptide-MHC interaction rules
• High-throughput antigen discovery platforms
• Autoimmune disease immunotherapy
• T cell repertoire dynamics in disease
• Lentiviral vector engineering

His work spans immunology, computational biology, and systems biology, with publications covering antigen discovery, T cell engineering, and disease-specific immunological mechanisms. The lab develops technologies to predict TCR ligands and modulate immune responses through synthetic receptors. Contact: joglekar@pitt.edu