Alexandra Rojek

Alexandra Rojek, MD is an Instructor in the Department of Medicine-Hematology and Oncology at the University of Chicago. She is a hematologist/oncologist specializing in the care of adults with lymphoma, with particular expertise in non-Hodgkin lymphomas, Hodgkin lymphoma, T cell lymphomas, and the role of stem cell transplantation. Dr. Rojek has a significant focus on chimeric antigen receptor (CAR) T-cell therapy for lymphoma patients.

Dr. Rojek's research focuses on identifying immunology mechanisms underlying the success of cellular therapies and developing strategies to improve cellular therapy efficacy. Her work spans lymphoma treatment, CAR T-cell therapy, and myeloid malignancies, with particular emphasis on clinical outcomes, prognostic markers, and real-world evidence. She has published extensively on cellular therapies, lymphoma treatment protocols, and CNS involvement in lymphoma, with her work appearing in high-impact journals including Blood, Blood Cancer Journal, and Clinical Lymphoma Myeloma and Leukemia.

Her publication record shows increasing productivity since 2019, with significant contributions in 2022 (5 publications), 2024 (4 publications), and a 2025 publication. Her research demonstrates a clear trajectory from basic science investigations (including protein aggregation studies from her earlier career) toward clinical hematology/oncology with a focus on innovative cellular therapies.

Dr. Rojek has collaborated with numerous researchers across multiple institutions, particularly with colleagues at the University of Chicago including Patel AA, Riedell PA, Nawas MT, and others. Her work spans both laboratory research and clinical investigations, demonstrating a translational approach to improving outcomes for patients with hematologic malignancies.