Alexander Revzin

Alexander Revzin, Ph.D., is a Professor of Biomedical Engineering at Mayo Clinic in Rochester, Minnesota, with a primary appointment as a Consultant in the Department of Physiology & Biomedical Engineering and a joint appointment in the Division of Gastroenterology and Hepatology, Department of Internal Medicine. He leads the Cellular Microsystems and Biosensors Laboratory, a multidisciplinary team developing microphysiological systems (organs-on-chip) to study liver fibrosis, stem cell biology, and biosensor applications.

• Department: Department of Physiology & Biomedical Engineering
• School: Mayo Clinic College of Medicine and Science
• Research Lab: Cellular Microsystems and Biosensors Laboratory
• Email: revzin.alexander@mayo.edu

Dr. Revzin's research lies at the intersection of engineering and biology, with a focus on microfabrication, microfluidics, biosensors, and regenerative medicine. His lab develops innovative platforms for cell cultivation and analysis, including liver-on-chip devices, stem cell spheroid systems, and biosensors for inflammatory cytokines and metabolites. These tools aim to model liver injury, improve stem cell differentiation, and enable point-of-care diagnostics, particularly for infectious diseases and liver conditions.

The 15 most recent publications (2023–2025) reflect a strong trend toward personalized medicine, organ-on-chip modeling, and biosensor integration. Key themes include microencapsulation of stem cell-derived tissues, microfluidic organoids for cancer therapy testing, extracellular vesicle analysis, and real-time monitoring of cellular function. His work spans high-impact journals in bioengineering, materials science, and translational medicine.

Scientific awards and professional recognition include:

• Fellow, American Institute for Medical and Biological Engineering (AIMBE), 2015
• Program Director, Nano-Biosensing, National Science Foundation, 2013–2014
• Chancellor’s Fellow, University of California, 2012
• Associate Editor, Microsystems & Nanoengineering (Nature group journal), 2014–present

Dr. Revzin actively mentors a large team of researchers and students, with frequent co-authorship from lab members such as Gwon K, de Hoyos-Vega JM, Gonzalez-Suarez AM, and Stybayeva G. His lab is equipped for microfabrication, cell culture, and biosensor development, supporting both basic and translational research. While no explicit grant details are listed, his leadership in major journals and multi-institutional collaborations suggests strong funding support.

The Cellular Microsystems and Biosensors Laboratory fosters interdisciplinary collaboration, integrating mechanical, chemical, and biomedical engineers with chemists and biologists to advance regenerative medicine and diagnostic technologies.