جستجوی استاد راهنمای دانشگاهی

Prof. Heike Krebber is a Professor for Molecular Genetics at Georg-August University Göttingen, Germany. Her research focuses on mRNA quality control and non-coding RNA functions, using the model organism Saccharomyces cerevisiae. She has held positions at the DKFZ (Heidelberg), Harvard Medical School, and Philipps-Universität Marburg. Her work addresses how mRNA processing defects contribute to diseases like cancer and neurodegeneration. Education & Positions: PhD (1996), Deutsches Krebsforschungszentrum Heisenberg Fellow (2006) Habilitation in Molecular Biology (2005) Professor since 2010 at Georg-August University Research Interests: Her lab investigates: RNA quality control mechanisms ensuring proper mRNA maturation and export Functions of non-coding RNAs (e.g., lncRNAs in iron metabolism and telomerase) Ribosome assembly and translation termination pathways Stress-induced bypass of mRNA quality control Awards: Heisenberg Fellowship (2006) Grants & Teams: Leads the Molecular Genetics group at the Institute for Microbiology and Genetics. Collaborates with the IMPRS Molecular Biology and GZMB (Molecular Biology of Cells) programs. Labs & Affiliations: Her group is part of the GGNB network, focusing on Microbiology and Biochemistry. The lab’s work spans fundamental molecular mechanisms with translational disease relevance.

• mRNA Quality Control
• ncRNA Functions
• Molecular Biology
• +۳ مورد دیگر

Marcel Köhn is a Researcher and head of an independent junior research group at the Medical Faculty of Martin Luther University of Halle-Wittenberg since 2016. He has been the scientific coordinator of the Research Training Group (RTG) 1591 “Posttranscriptional Control of Gene Expression” since 2015. He earned his PhD in Biochemistry from MLU in 2015. Education: Bachelor/Master in Biochemistry, MLU Halle PhD in Biochemistry, MLU Halle (2015) His research focuses on non-coding RNAs in cardiovascular and neoplastic diseases, particularly analyzing RNA-binding proteins like SRSF1 and their intrinsically disordered regions (IDRs). His work bridges cellular-level studies of SRSF1 function and molecular mechanisms of RNA-protein interactions involving IDRs, aiming to elucidate how disorder impacts RNA-binding protein roles. Key publications include studies on Y3 ncRNA’s role in histone mRNA maturation and broader investigations into non-coding RNA functions. His research integrates posttranscriptional control mechanisms with clinical disease contexts. He leads a junior research group focused on RNA biology within the Medical Faculty’s infrastructure. No specific grants or awards are explicitly listed in the provided text.

• Non-coding RNAs
• Cardiovascular Diseases
• Neoplastic Diseases
• +۳ مورد دیگر

Dagmar Beier is a Lecturer at the Chair of Microbiology, Biocenter, University of Würzburg. Her research focuses on non-coding RNA-mediated gene regulation in bacterial pathogens, particularly Neisseria gonorrhoeae and Helicobacter pylori, with emphasis on two-component systems, acid adaptation, and virulence mechanisms. Education: PhD in Biochemistry (University of Würzburg, 1992) Postgraduate studies in Biochemistry (University of Würzburg, 1989-1992) Studies of Chemistry (University of Würzburg, 1983-1989) Her work spans sRNA and antisense RNA functions in bacterial stress responses, phase variation, and mRNA turnover. Key publications highlight regulatory networks in Neisseria gonorrhoeae's metabolic pathways and Helicobacter pylori's acid adaptation systems. Recent studies demonstrate her expertise in RNA chaperone interactions and flagellar gene regulation in Listeria monocytogenes. She leads projects analyzing ncRNA roles in pathogenic bacteria, with a strong record in senior authorships and collaborative research at the University of Würzburg. Contact: dagmar.beier@uni-wuerzburg.de | Room C240 | Office hours: Tuesdays 10-11 a.m.

• Microbiology
• Molecular Biology
• Gene Expression Regulation
• +۳ مورد دیگر

Peter Baumann is a Professor at the Institute for Molecular Biology (IMB) within Johannes Gutenberg University Mainz, Germany. His laboratory investigates fundamental mechanisms of chromosome biology with emphasis on telomere maintenance, meiotic processes, and evolutionary consequences of hybridization. The Baumann Lab operates from Ackermannweg 4, 55128 Mainz, and maintains active collaborations through DFG-funded initiatives including the SFB1361 consortium and the GeneEvo Research Training Group. Research interests center on three interconnected domains: (1) Telomerase biogenesis focusing on ncRNA subunit processing and regulatory mechanisms controlling telomerase activity; (2) Molecular triggers of parthenogenesis and clonal reproduction in vertebrates, particularly using Aspidoscelis lizards as model systems; (3) Hybridization and polyploidy effects on gene expression and fitness. His work bridges molecular mechanisms with evolutionary outcomes through innovative experimental approaches including in vitro evolution assays and synthetic speciation. Analysis of recent publications reveals consistent focus on telomerase RNA processing mechanisms across multiple model organisms, with increasing emphasis on evolutionary genomics of asexual vertebrate lineages. Key methodologies include fission yeast genetics, RNA biochemistry, and comparative cytogenetics of reptilian systems. EMBO Membership (2019) DFG Research Training Group 'Gene Regulation in Evolution' (GenEvo) Funding Baumann actively supervises doctoral researchers including Valentine Patterson and Lukas Ende (both joined 2019), with recent successful thesis defenses by Cameron. His laboratory participates in major collaborative grants including the SFB1361 consortium investigating chromosome organization. The research environment includes established protocols for fission yeast studies and specialized facilities for reptilian genomics. Lab activities documented through group photos, field excursions (lizard hunting, canoe trips), and scientific celebrations reflect an integrated research community focused on chromosome biology from molecular to evolutionary scales.

• Telomerase Biogenesis
• Chromosome End Protection
• Meiosis and Parthenogenesis
• +۴ مورد دیگر

Steve Hoffmann is a Group Leader at the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) , specializing in bioinformatics and genomics. His research focuses on RNA-Seq analysis workflows, p53 gene regulatory networks, and epigenetic aging mechanisms through projects like de.STAIR (BMBF 031L016A) and DFG FI 1993/2-1 . Hoffmann collaborates with the RNA Bioinformatics Center (RBC) and integrates multiomics approaches for cancer and aging studies. Education: Not explicitly detailed but inferred from research leadership and publications. Projects: de.STAIR for RNA-Seq workflows; DFG FI 1993/2-1 dissecting p53 networks; contributions to DNA methylation, circRNA detection, and aging genomics His research interests span bioinformatics tool development, gene regulation, epigenetics, and aging. Hoffmann’s recent articles emphasize nonlinear aging patterns, chromatin remodeling, and tumor suppression mechanisms. He leads a team of doctoral candidates and postdocs, including Maja Kinga Olecka and Omid Omrani, and contributes to open-source platforms like Galaxy. Hoffmann’s work addresses gaps in p53 target gene regulation and aging-related epigenomic changes, supported by grants from the DFG and BMBF. Hoffmann’s scientific contributions include tools like metilene and DARIO for DNA methylation and ncRNA analysis. His advising involves mentoring students in computational biology and aging research. Collaborations with the Leibniz Research Alliance Resilient Ageing and Balance of the Microverse DFG Cluster of Excellence highlight his institutional affiliations. Hoffmann’s labs integrate next-generation sequencing, proteomics, and life science computing facilities at FLI, focusing on data-driven workflows for aging and cancer studies.

• Bioinformatics
• Genomics
• Cancer Research
• +۲ مورد دیگر

Peter Florian Stadler is a Professor of Bioinformatics at the University of Leipzig since 2002 and Director of the Interdisciplinary Center for Bioinformatics (IZBI) since 2023. He holds affiliations with the Max Planck Institute for Mathematics in the Sciences (scientific member since 2009), the Austrian Academy of Sciences (corresponding member since 2010), and the Santa Fe Institute (external member since 1994). Doctorate in Chemistry (University of Vienna, 1990) Habilitation in Theoretical Chemistry (University of Vienna, 1994) His research focuses on Bioinformatics , Computational Biology , and Evolutionary Dynamics , with specific interests in RNA structure prediction , non-coding RNA , and genome-wide data analysis . Recent work involves developing ViennaRNA Package tools and studying translational control mechanisms in melanoma. Professional milestones include: Co-development of Vienna RNA Package , FRANz (phylogenetic tree reconstruction), code2aln (alignment tools) Key contributions to RNA gene finding algorithms and ncRNA family characterization Honors: Corresponding member, Austrian Academy of Sciences (2010) Honorary professor, Faculty of Science, Bogota (2018)

• Bioinformatics
• Computational Biology
• RNA Biology
• +۴ مورد دیگر

Lars Maegdefessel is a Professor of Molecular Vascular Medicine at the Technical University Munich (TUM), School of Medicine and Health. He leads the Experimental Vascular Medicine unit at Klinikum rechts der Isar and serves as a DZHK Junior Group Leader. His research focuses on the therapeutic and biomarker potential of non-coding RNAs in vascular diseases including atherosclerosis, aortic aneurysm, and related vascular pathologies. Dr. Maegdefessel's research interests center on the role of non-coding RNAs in vascular diseases, with particular focus on the vulnerability of atherosclerotic vascular lesions and the progression and rupture of abdominal aortic aneurysms. His laboratory utilizes unique human biobank materials and various pre-clinical experimental models to investigate novel molecular approaches for combating cardiovascular diseases. His work spans from basic research on microRNAs, long non-coding RNAs, and circular RNAs to translational applications in vascular medicine. Analysis of Dr. Maegdefessel's publication record reveals a strong focus on non-coding RNA mechanisms in vascular pathology, with particular emphasis on atherosclerosis stabilization, aneurysm development, and vascular inflammation. His research has evolved from basic miRNA characterization to sophisticated therapeutic applications including targeted delivery systems and novel biomarker discovery. The publications demonstrate a consistent trajectory toward clinical translation of RNA-based vascular therapeutics. ERC Consolidator Grant (2023) Russel Ross Award from American Heart Association (2023) Heisenberg Professorship of German Research Foundation (2016) Werner Risau Award of American Heart Association (2016) ERC Starting Grant (2015) Prince Daniel Research Award of Swedish Heart and Lung Foundation (2014) Ragnar Söderberg Fellowship in Medicine (2014) Dr. Maegdefessel's research program includes extensive collaboration with international teams and utilizes advanced methodologies including RNA sequencing, microarrays, proteomics, and epigenomic analyses. His laboratory investigates ncRNA function in human vascular tissues and pre-clinical models, with recent work focusing on artery-on-a-chip technology and novel therapeutic delivery systems for vascular applications.

• vascular disease
• atherosclerosis
• aortic aneurysm
• +۴ مورد دیگر