- Space Biology
- Microgravity Research
- Neurobiology
- +۵ مورد دیگر
Marcel Egli serves as Head of the Institute for Medical Technology (IMT) at the Lucerne University of Applied Sciences and Arts (HSLU) within the School of Engineering & Architecture. His institute combines the Center of Competence in Bioscience and Medical Engineering, the Space Biology Group, and the User Support and Operational Center BIOTESC that serves the European Space Agency (ESA). The IMT offers study programs and complementary post-graduate courses in medical technology. Dr. Egli's research focuses on cellular mechanisms of mechanosensation induced by mechanical unloading (weightlessness). His academic journey began with training as a precision mechanic, followed by a master's degree in zoology from the University of Berne and multidisciplinary graduate studies in medicine and biology. He conducted postdoctoral research at the University of Melbourne and Florida State University, where he became Associate Faculty studying secretory rhythms of hormones in mammals. His appointment to lead the Space Biology Group at ETH Zurich brought him back to Switzerland, where he received his Venia Legendi in space biology before moving his research group to Lucerne to establish the Institute of Medical Engineering. Egli's publication record demonstrates a clear trajectory from neurobiology and neuro-endocrinology toward space biology research. His recent work utilizes diverse research platforms including parabolic flight maneuvers, sounding rockets, and International Space Station laboratories to investigate cellular responses to microgravity. His research spans cellular mechanosensation, calcium signaling, tissue engineering, and the development of space-compatible biomedical instrumentation. Dr. Egli has led numerous significant projects including Space Bioreactor development, COSMOS Data Cockpit for Personalized Medicine, research on astronauts' low back pain, and the CaSiPaC project studying calcium signaling during parabolic flight in chondrocytes. His work has received support from space agencies including ESA and the Canadian Space Agency. The Institute for Medical Technology under Egli's leadership operates as a multidisciplinary hub connecting space research with terrestrial medical applications. His team develops technologies that function in both space environments and Earth-based clinical settings, with particular emphasis on understanding how mechanical unloading affects biological systems at the cellular level. This research has implications for both space medicine and understanding terrestrial conditions like osteoporosis and muscle atrophy.