Transcriptomics Professors and Supervisors in Sweden

Mattias Aleniusمشاهده پروفایل

استاد

Umea UniversitySweden

Mattias Alenius is a full Professor at the Department of Molecular Biology , Umeå University , Sweden, where he heads an active research group investigating the molecular and cellular bases of olfaction and taste. His laboratory exploits the genetic tractability of Drosophila and the physiological relevance of mouse models to uncover conserved mechanisms that govern sensory neuron specification, ciliary trafficking, and systemic feedback control of sensory perception. Research Focus His team is particularly interested in: Homeostatic control of neuronal activity and how its failure leads to neurodegenerative diseases. Olfactory and gustatory circuits —leveraging the numerically simple and genetically powerful Drosophila system. Hedgehog signaling and its role in ciliary transport of odorant receptors across species. Inter-organ communication , including gut-to-brain signaling that modulates feeding behavior. Epigenetic inheritance , exploring how paternal diet shapes chromatin states and metabolic phenotypes in offspring. Methodologically, the group integrates in vivo genetics, single-cell transcriptomics, live-cell imaging, cryo-EM, and behavioral assays to dissect these processes from molecule to organism. Scientific Output & Trends Across more than two decades, Prof. Alenius has produced a steady stream of high-impact publications in journals such as Nature Communications , Cell Reports , PNAS , Cell , PLoS Biology , and BMC Biology . His recent work (2022-2024) increasingly centers on nutrient sensing and gut-brain taste modulation , while earlier studies laid the groundwork for understanding ciliary dynamics and transcriptional codes specifying olfactory receptor choice. Collectively, the publications reveal a trajectory from developmental specification of sensory neurons to systemic metabolic control, unified by a focus on hedgehog signaling , cilia-mediated processes , and transcriptional/epigenetic mechanisms . Labs & Teams Prof. Alenius leads the Group Mattias Alenius located in rooms 6K and 6L within the hospital area at Umeå University. The group participates in the university’s Department of Molecular Biology and collaborates extensively across neuroscience and metabolism communities both nationally and internationally. Contact Email: mattias.alenius@umu.se Phone: +46 90 786 91 57

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Peter Lindمشاهده پروفایل

دانشیار

Umea UniversitySweden

Peter Lind is an Associate Professor at the Department of Molecular Biology, Umeå University, Sweden. He leads the Lind Lab, focusing on experimental evolution and mathematical modeling of bacterial biofilm formation and antibiotic resistance, particularly in Pseudomonas and Acinetobacter species. His work bridges evolutionary biology with clinical applications to address antimicrobial resistance challenges. Contact: Email peter.lind@umu.se , Phone +46 90 786 89 80 Location: 6K/6L, Hospital Area, Umeå University Research Interests: The group studies evolutionary pathways in bacteria under stressors like antibiotics, aiming to predict and redirect evolution toward dead ends. Key areas include: Biofilm dynamics and extracellular matrix formation Antibiotic resistance mechanisms and multi-resistance evolution Mathematical modeling of molecular networks Clinical translation for infection biology and drug development Publication Trends: Over the past five years, his work spans hyperbaric oxygen therapy applications (for ARDS, long COVID, and ulcerative colitis), diving medicine (barotrauma, pulmonary edema), and advanced imaging techniques (PET, MRI, Doppler ultrasound). The research emphasizes interdisciplinary approaches combining clinical practice, computational modeling, and experimental evolution. Labs & Collaborations: Lind Lab collaborates with clinical teams at Umeå University Hospital, contributes to the UCMR program as education director, and develops open-source tools for diving-related medical diagnostics. Their work informs antibiotic stewardship and evolutionary prediction frameworks.

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Sébastien de La Forest Divonneمشاهده پروفایل

پژوهشگر ارشد

Umea UniversitySweden

Sébastien de La Forest Divonne is a postdoctoral fellow at Umeå University in the Department of Molecular Biology, working within Professor Ryo Morimoto's research group at the Hospital area campus (locations 6K and 6L) in Umeå, Sweden. His position focuses exclusively on advanced research in invertebrate immune systems. He earned his PhD from the University of Perpignan Via Domitia (France) at the IHPE laboratory, where he characterized hemocyte diversity in the Pacific oyster ( Crassostrea gigas ) through integrated transcriptomic, cytological, and functional analyses, including investigations into bacterial infection impacts on cellular dynamics. Dr. de La Forest Divonne's current research centers on hematopoiesis in the freshwater snail Biomphalaria glabrata —a critical intermediate host for human Schistosoma parasites. Using single-cell RNA sequencing (scRNA-seq) and CRISPR-Cas9 functional genomics, he maps hemocyte lineage trajectories by disrupting transcription factors and validates differentiation mechanisms. Concurrently, he studies fibrinogen-related proteins (FREPs), examining their diversification mechanisms and roles in microbial recognition and parasite clearance, advancing understanding of invertebrate immune evolution. Scientific Awards: No awards were documented in the source materials. Advising and Grants: Information regarding student supervision or research funding sources was not provided in available records. Laboratories and Teams: He actively contributes to the Ryo Morimoto Lab at Umeå University, collaborating on host-pathogen interaction studies with emphasis on immune system dynamics in invertebrate models.

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Pauliina Damdimopoulouمشاهده پروفایل

استاد

Karolinska InstitutetSweden

Professor Pauliina Damdimopoulou is a leading researcher in reproductive biology at Karolinska Institutet's Department of Women's and Children's Health. She leads the "Chemicals and female fertility" research group, investigating how environmental chemicals impact female fertility and ovarian function. With over 15 years of experience in endocrinology, reproductive biology and toxicology, she has established herself as an expert in reproductive toxicology and currently serves as ERC ambassador and Professor since 2025. Her educational background includes: Docent (Associate Professor) in endocrine physiology (2015, University of Turku, Finland) Docent in toxicology (2021, Karolinska Institutet) Professor Damdimopoulou's research focuses on environmental exposures like industrial chemicals and air pollution and their links to reduced fertility in women. She's particularly interested in how these exposures affect ovaries and oocytes, which form before birth and represent a finite, non-renewable resource. Her work combines epidemiological studies with controlled in vitro exposure studies to unravel molecular mechanisms by which chemicals affect ovarian function, with the ultimate goal of developing better tools for reproductive toxicity testing. Her recent publications (2023-2025) show a strong interdisciplinary focus on how specific chemical classes (phthalates, PFAS, persistent organic pollutants) affect ovarian function, follicular development, and female fertility. There's a clear trend toward developing better in vitro models for reproductive toxicity testing, mapping molecular pathways affected by environmental chemicals, and translating these findings into improved regulatory frameworks. Her work bridges epidemiology, molecular biology, toxicology, and clinical reproductive medicine. Her scientific awards include: ERC Consolidator Grant (2023) - EUR 2 million for the SAFER project (SAfeguarding female FERtility-development of human-relevant in vitro tools for reproductive toxicity) Professor Damdimopoulou has extensive experience in academic mentoring, having supervised numerous undergraduate students through laboratory training, MSc thesis projects, and served as main supervisor for multiple PhD students. She has formal training in higher education pedagogy and doctoral student supervision. Her research is supported by significant grants including the ERC Consolidator Grant for the SAFER project, which aims to develop human-relevant in vitro tools for reproductive toxicity testing to replace current animal-based methods. She leads the "Chemicals and female fertility" research group at Karolinska Institutet and co-leads the Environmental Endocrinology Focus Area of the European Society of Endocrinology. Her lab develops advanced tissue culture models including 3D spheroid systems and works with human ovarian tissue samples to study chemical effects on reproductive function. The group maintains active collaborations with researchers across Europe and participates in major research initiatives focused on endocrine disruption and reproductive health.

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Sam Dupontمشاهده پروفایل

مدرس

University of GothenburgSweden

Marine Biology
Ocean Acidification
Climate Change Impacts on Marine Ecosystems
+۴ مورد دیگر

Sam Dupont serves as a Lecturer in the Department of Biology and Environmental Sciences at the University of Gothenburg, conducting research at the Kristineberg Marine Research Station. His work focuses on experimental marine physiology under global change scenarios, with particular expertise in ocean acidification impacts across diverse marine taxa. Dr. Dupont's research centers on physiological and ecological responses to environmental stressors, especially ocean acidification and multi-stressor interactions. His investigations span molecular mechanisms to ecosystem-level consequences, with significant contributions to understanding calcification processes, transgenerational plasticity, and bioluminescence systems in marine invertebrates. Recent work examines sex ratio shifts in bivalves under acidification and local adaptation in sea urchin populations. Analysis of Dr. Dupont's 2023-2025 publications reveals consistent output in high-impact journals, with strong emphasis on experimental marine ecology combining field and laboratory approaches. His work demonstrates increasing international collaboration, particularly with researchers in tropical and polar regions, addressing climate change impacts across diverse marine ecosystems from coral reefs to Antarctic habitats. Dr. Dupont actively supervises graduate students and incorporates research into teaching through field-based courses at Kristineberg. His laboratory maintains active collaborations across 12 countries, with research funded through competitive national and international grants. Current projects focus on multi-stressor interactions, local adaptation mechanisms, and the physiological basis of climate resilience in marine organisms. Based at the Kristineberg Marine Research Station, Dr. Dupont's work benefits from direct access to diverse coastal habitats and state-of-the-art experimental facilities. His research group participates in international monitoring networks and contributes to climate change assessment frameworks, bridging fundamental science with conservation applications.

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Theodora Kunovac Kallakمشاهده پروفایل

دانشیار

Uppsala UniversitySweden

Theodora Kunovac Kallak serves as Associate Professor and Senior Lecturer at Uppsala University's Department of Women's and Children's Health within the Faculty of Medicine. She holds multiple leadership roles including Program coordinator for the Biomedical Laboratory Science Programme, director of Precision Medicine Centre Uppsala (PMCU), and leads laboratory operations at KBH Rudbeck while managing the department's Clinical Research Office. Dr. Kunovac Kallak's research program centers on experimental obstetrics and gynecology with particular emphasis on cancer treatment effects on reproductive health. Her work spans multiple interconnected domains: Long-term impacts of cancer therapies on sexual function and fertility Maternal health during pregnancy and its relationship to child development Environmental exposures (particularly phthalates) and reproductive system function Genetic and epigenetic factors in pregnancy outcomes Maternal mental health and peripartum depression Analysis of her recent publications reveals a strong methodological diversity combining population-based register studies, in vitro cellular models, and molecular analyses. Her research consistently examines how maternal conditions and environmental exposures affect both immediate pregnancy outcomes and long-term child health trajectories, with growing emphasis on precision medicine approaches to women's reproductive health. As director of the Precision Medicine Centre Uppsala, Dr. Kunovac Kallak oversees initiatives integrating genomic, clinical, and environmental data to develop personalized approaches to women's and children's healthcare. Her leadership of the Clinical Research Office indicates responsibility for methodological oversight across multiple departmental studies, while her role as Program coordinator demonstrates commitment to training the next generation of biomedical laboratory scientists.

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Andreas Wallbergمشاهده پروفایل

پژوهشگر

Uppsala UniversitySweden

Andreas Wallberg is a Researcher at Uppsala University's Department of Medical Biochemistry and Microbiology, specializing in Genetics and Genomics within the Faculty of Medicine. His work spans multiple research areas including evolutionary biology, population genetics, and genomics, with particular focus on adaptation mechanisms in diverse organisms ranging from honeybees to marine species. Wallberg maintains an active research profile with numerous high-impact publications in leading scientific journals. Wallberg's research interests center on understanding evolutionary processes through genomic analysis. His work explores how organisms adapt to environmental challenges, including high-altitude habitats, brackish water environments, and polar conditions. His research combines molecular techniques with computational approaches to unravel the genetic basis of adaptation across diverse species. His laboratory work spans from honeybee genomics to marine organism evolution, demonstrating a broad interdisciplinary approach to evolutionary questions. Analysis of Wallberg's recent publications reveals a strong focus on comparative genomics and evolutionary adaptation. His work demonstrates expertise in analyzing complex genomic datasets to identify loci responsible for environmental adaptation across diverse species. The research spans terrestrial organisms like honeybees adapting to high altitudes and marine organisms adapting to specific oceanic conditions, showing Wallberg's versatile approach to evolutionary genomics questions. Wallberg serves in multiple administrative capacities at Uppsala University, including as Chemical Safety Officer, Environmental Representative, and Fire Protection Representative for the Department of Medical Biochemistry and Microbiology. His collaborative research network spans multiple institutions and countries, as evidenced by the international authorship of his publications.

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Hirsh Koyiمشاهده پروفایل

پژوهشگر

Uppsala UniversitySweden

Hirsh Koyi is a Researcher affiliated with Uppsala University through the Centre for Research & Development at Region Gävleborg, focusing on clinical oncology and respiratory medicine. His work bridges hospital-based clinical research with academic investigation, primarily conducted at Gävle Hospital. His research spans lung cancer diagnostics, pleural effusion analysis, pharmacogenomics of chemotherapy toxicity, and swallowing dysfunction in respiratory diseases. Key interests include: Non-small cell lung cancer molecular subtyping and prognostic biomarkers Genetic variants influencing gemcitabine/carboplatin toxicity Dysphagia mechanisms in COPD and post-COVID recovery Ethnic disparities in mesothelioma and lung cancer outcomes His methodology integrates genomic analysis, clinical pharmacology, and patient-centered outcomes assessment. Recent publications demonstrate consistent focus on translational oncology, with trends toward personalized treatment prediction using gene expression and pharmacogenomic markers. His collaborative work frequently addresses real-world clinical challenges in elderly cancer patients and post-ICU rehabilitation. Koyi maintains active clinical research collaborations across Swedish medical centers, particularly in pharmacokinetic studies and respiratory complication management. His work appears in journals spanning oncology, respiratory medicine, and analytical pharmacology.

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Dorothe Spillmannمشاهده پروفایل

مدرس ارشد

Uppsala UniversitySweden

Dorothe Spillmann serves as a Senior Lecturer at the Department of Medical Biochemistry and Microbiology within the Faculty of Medicine at Uppsala University. With a research career spanning several decades, she has established herself as a prominent figure in glycobiology with particular expertise in glycosaminoglycan structure and function. Dr. Spillmann's research focuses on the structural and functional aspects of heparan sulfate and chondroitin sulfate, examining how specific modifications to these molecules influence cellular processes. Her work bridges fundamental biochemistry with clinical applications, particularly in cancer biology where she investigates how glycosaminoglycan alterations affect tumor progression, metastasis, and cellular signaling pathways. She has made significant contributions to understanding the role of specific sulfation patterns in cell behavior, especially in melanoma and breast cancer contexts. Analysis of her publication record reveals a consistent trajectory of high-impact research in glycosaminoglycan biology. Her most recent work examines transcriptomic changes in melanoma cells modified by heparanase, the role of chondroitin sulfate in regeneration processes, and how specific enzymes that modify heparan sulfate affect cancer cell migration. Her research demonstrates expertise across multiple methodologies including molecular biology, biochemical analysis, and mass spectrometry-based approaches for characterizing glycosaminoglycan structures. Dr. Spillmann has maintained extensive collaborative networks both within Uppsala University and internationally, contributing to diverse research projects that examine glycosaminoglycan biology in cancer, development, and infectious disease contexts. Her work continues to advance our understanding of how these complex carbohydrates regulate fundamental cellular processes with implications for human health and disease.

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John Inge Johnsenمشاهده پروفایل

دانشیار

Karolinska InstitutetSweden

John Inge Johnsen is a Principal Researcher and Docent (Associate Professor) at Karolinska Institutet, working within the Department of Women's and Children's Health, specifically in Pediatric Oncology and Pediatric Surgery. He leads the Per Kogner and John Inge Johnsen research group, which focuses on childhood neural tumors, particularly medulloblastoma and neuroblastoma. Dr. Johnsen received his PhD from the University of Tromsø, Norway in 1994 under the supervision of Professor Terje Traavik, with his thesis focusing on polyomaviruses. After completing his PhD, he pursued cancer biology research at the University of California, Irvine in Professor Eric Stanbridge's lab, studying p53 and its effects on cancer development. He later joined Professor Per Kogner's research group at Karolinska Institutet as a postdoctoral fellow, where he helped build the childhood neural tumor research consortium. He became an Associate Professor at Karolinska Institutet in 2010. His research focuses on identifying new treatment options for children with medulloblastoma and neuroblastoma to improve survival rates, reduce treatment-related complications, and enhance quality of life. His group applies various Omic techniques to characterize the molecular landscape of malignant and non-cancerous cells within the tumor microenvironment. They use translational approaches with preclinical in vivo models to identify drugs targeting specific biological aberrations in cancer cells. The research group has published extensively on childhood neural tumors, with recent work focusing on genomic analysis, single-cell transcriptomics, tumor microenvironment characterization, and drug discovery. Their publications reveal a strong emphasis on understanding tumor heterogeneity, cancer stem cells, and molecular pathways driving tumor progression. Dr. Johnsen has secured significant research funding, including grants from Barncancerfonden and the Swedish Cancer Society for projects titled 'New treatment options for childhood neural tumors' and 'Identifying and overcoming mechanisms of treatment resistance in patients with neuroblastoma.' His work demonstrates a commitment to translational research that bridges basic science discoveries with clinical applications, aiming to develop more effective therapies for children with challenging neural tumors.

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Lalit Kumar Parameswaran Graceمشاهده پروفایل

دانشیار

Karolinska InstitutetSweden

Lalit Kumar Parameswaran Grace serves as a Docent (Associate Professor) and Principal Researcher at Karolinska Institute. He is affiliated with the Department of Women's and Children's Health, specifically within the Division for Neonatology, Obstetrics, Gynaecology and Reproductive Health. Dr. Grace leads the Experimental Research team under Kristina Gemzell Danielsson's Reproductive Health/Reproductive Medicine research group, focusing on translational research in reproductive medicine. Principal Researcher, Department of Women's and Children's Health, Karolinska Institutet (2022-present) Docent, Karolinska Institutet (2021) Dr. Grace's primary research interests center around understanding the molecular and cellular mechanisms involved in various gynecological conditions. His laboratory employs advanced techniques including 2D and 3D cell culture, single cell RNA sequencing, smartseq2/smartseq3, spatial transcriptomics and bioinformatic tools to investigate physiological and pathophysiological conditions affecting female fertility. His work specifically targets endometrial regeneration and receptivity for infertility management, developing non-invasive molecular methods to identify receptive endometrium and good quality embryos for clinical use in assisted reproductive technology. His recent publications (2022-2024) demonstrate a strong focus on molecular diagnostics for reproductive disorders, with particular emphasis on endometriosis mechanisms, endometrial receptivity biomarkers, and the effects of viral infections like SARS-CoV-2 on pregnancy outcomes. His research bridges basic science with clinical applications, aiming to translate molecular findings into practical diagnostic tools for fertility clinics. Dr. Grace leads the Experimental Research team at Karolinska Institute, working within a larger collaborative framework that includes clinicians, basic science researchers, and global reproductive health specialists. The team's work on endometrial receptivity, embryo quality assessment, and endometriosis mechanisms represents a significant contribution to advancing reproductive medicine through molecular diagnostics and translational research.

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Ferdinand von Waldenمشاهده پروفایل

استادیار

Karolinska InstitutetSweden

Ferdinand von Walden is an Assistant Professor and Docent at Karolinska Institutet's Department of Women's and Children's Health, where he leads Thomas Sejersen's Neuromuscular Diseases research group. He holds a dual clinical role as a pediatric resident at Astrid Lindgren Children's Hospital. His academic credentials include: Docent (Karolinska Institutet, 2025) PhD in Physiology and Pharmacology (Karolinska Institutet, 2015) Medical Degree (Karolinska Institutet, 2009) Master of Medical Science (Karolinska Institutet, 2007) Dr. von Walden leads multidisciplinary research in muscle physiology with emphases on: Molecular mechanisms of ribosome biogenesis in muscle adaptation Exercise interventions for cerebral palsy patients Epigenetic regulation of muscle growth Systemic effects of endurance/resistance training His work bridges clinical pediatrics with fundamental muscle biology. His publication record demonstrates consistent focus on muscle adaptation mechanisms across populations. Recent work (2022-2025) shows strong trends toward: Advanced molecular analysis of exercise responses Clinical translation in cerebral palsy rehabilitation Innovative biomarker discovery using omics technologies Integration of basic muscle physiology with clinical applications He leads several funded projects including studies on ribosome biogenesis, resistance training in children, and exercise physiology in cerebral palsy. His research team includes 6 PhD students and 2 postdoctoral fellows. He collaborates extensively with Linköping University and has secured significant funding, including a SEK 10 million grant from Promobilia Foundation for research on motor impairments in children.

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