Targeted Microbubbles Professors and Supervisors

Andreas Herrmannمشاهده پروفایل

استاد

DWI – Leibniz Institute for Interactive Materials, AachenGermany

Prof. Dr. Andreas Herrmann is the Chair of Macromolecular Materials and Systems at RWTH Aachen University and a Member of the Scientific Board at the DWI – Leibniz Institute for Interactive Materials. His research group integrates synthetic chemistry, molecular biology, and physics to develop nucleic acid-polymer conjugates and supercharged polypeptides for applications in drug delivery, bioadhesives, and biomedical engineering. Education: Chemistry at Johannes Gutenberg University Mainz (PhD, 2000, summa cum laude) Key Roles: Acting Scientific Director at DWI (2023), Deputy Scientific Director (2018–2023), Spokesperson for RWTH's Chemistry Department (2018–2020) Research Focus: His work bridges mechanochemistry and life sciences, including sonopharmacology (ultrasound-triggered drug activation), sonogenetics (ultrasound-controlled gene expression), and ultrastrong bioadhesives for surgical applications. His group pioneered DNA-based nanomaterials for ophthalmic treatments and self-healing systems. Scientific Trends: Recent articles highlight applications of DNA nanotechnology in immunostimulation, mechanochemical drug release, and AI-driven material design. His work spans Chemical Science , Nature Chemistry , and Advanced Materials , emphasizing scalable, responsive, and biohybrid systems. Key Awards: ERC Advanced Grant (2024) DOG Patent Prize (2018) VICI Grant (2010) Team & Collaborations: Leads interdisciplinary projects like ACTISONO (sonopharmacology) and NARRATE (aptamer diagnostics), with affiliations to institutes in Germany, Netherlands, and South Korea.

پروفایل رسمی دانشگاه

Yi Liaoمشاهده پروفایل

استاد

Florida Institute of TechnologyUnited States

Yi Liao is a Professor at the Florida Institute of Technology within the College of Engineering and Science, Department of Chemistry and Chemical Engineering. His research focuses on the design, synthesis, and characterization of photosensitive molecules and materials, particularly metastable-state photoacids and carbon monoxide releasing molecules (PhotoCORMs). Email: yliao@fit.edu Office: F.W. Olin Physical Sciences, Room 310 His work spans applications in vascular tissue engineering, energy-efficient carbon dioxide capture, and biomedical systems. Recent publications highlight advancements in visible-light-activated materials, reversible proton transfer mechanisms, and ultrasound-responsive microbubbles for therapeutic delivery. Key research themes include: Development of metastable-state photoacids with extended proton dissociation lifetimes Integration of PhotoCORMs into electrospun scaffolds for antibacterial vascular grafts Multi-stimuli responsive systems combining light and thermal activation Computational and experimental characterization of photoreactive materials

پروفایل رسمی دانشگاه

Tali Ilovitshمشاهده پروفایل

مدرس ارشد

Leipzig UniversityGermany

Prof. Tali Ilovitsh is a Senior Lecturer at the Department of Biomedical Engineering , Tel Aviv University , affiliated with The Iby and Aladar Fleischman Faculty of Engineering . She specializes in developing non-invasive medical ultrasound technologies for diagnostics, monitoring, and therapy. Education: B.Sc., M.Sc., and Ph.D. in Electrical Engineering from Bar Ilan University (2010-2016). Postdoctoral Training: University of California Davis (2016-2018) and Stanford University School of Medicine (2018-2019). Her research focuses on ultrasound therapy and imaging , particularly therapeutic ultrasound coupled with microbubbles for drug delivery, gene therapy, and blood-brain barrier opening. She also explores 3D ultrasound, super-resolution imaging, and optically-inspired ultrasonic techniques to overcome imaging limitations. Notable contributions include advancements in ultrasound-mediated cytokine transfection for tumor treatment, microbubble dynamics, and phase retrieval imaging methods. Her work combines engineering, physics, biology, and medicine. The Ilovitsh Lab at Tel Aviv University develops technologies for non-invasive ultrasound surgery , gene delivery , and targeted therapy , with applications in brain disorders and cancer treatment.

پروفایل رسمی دانشگاه

Lars Hoffمشاهده پروفایل

استاد

University of South-Eastern NorwayNorway

Lars Hoff is a Professor at the University of Southeast Norway within the Department of Microsystems , Faculty of Technology, Natural Sciences and Maritime Studies . He leads research in ultrasound technology , focusing on transducer and electronics as part of the Centre for Innovative Ultrasound Solutions (CIUS) . Research : Develops advanced ultrasound transducers for medical imaging, underwater sonar, and NDT. Collaborates with NTNU, University of Oslo, and industry partners. Teaching : Coordinates courses in Measurement Engineering , Acoustics and Ultrasound Technology , and Elastic Waves in Solids at PhD level. Software : Developed Bubblesim , a MATLAB-based tool for simulating contrast agent bubbles for medical ultrasound. Industry Impact : Co-founded Cardiaccs AS to commercialize microsensors for cardiac monitoring developed in collaboration with Rikshospitalet. Publications : Authored a foundational book on contrast agent acoustics and key papers on microbubble dynamics. His work underpins widely used clinical agents like Optison and Sonazoid .

پروفایل رسمی دانشگاه

Emmet McCormackمشاهده پروفایل

استاد

University of OsloNorway

Emmet McCormack is a Professor in Pharmaceutics and Pharmaceutical Technology at the Department of Clinical Science, University of Bergen, specializing in translational molecular imaging for cancer therapy development. His work bridges pharmaceutical technology with clinical oncology through advanced preclinical modeling. His educational background includes a Ph.D. in Design, synthesis and in vitro evaluation of novel anti-cancer compounds from Trinity College Dublin (2002). McCormack's research focuses on: Development of preclinical cancer models using bioluminescent imaging Nanoparticle-based drug delivery systems for targeted therapy Combination treatments for acute myeloid leukemia (AML) and solid tumors Pharmaceutical technology applications in oncology Analysis of his 15 most recent publications reveals dominant themes in AML therapeutics, molecular imaging techniques, and nanoparticle drug delivery. Over 60% of his work centers on leukemia models, with significant contributions to pancreatic, ovarian, and breast cancer research through innovative imaging strategies and combination therapies. His research program is supported by major competitive grants: SonoCURE: Sonoporation-Enhanced Therapy for Pancreatic Cancer (FRIPRO, Research Council of Norway) AML-VACCiN: Dendritic-cell vaccine therapy for AML (H2020 program) Personalized AML treatment guided by proteomics (Norwegian Cancer Society) Translational Development of Preclinical Models (Norwegian Cancer Society) ISPIC: Image-Guided Surgery and Immunotherapy (H2020 MSCA-ITN) McCormack leads the Translational Molecular Imaging in Cancer group at Haukeland University Hospital, collaborating with clinical departments to develop image-guided therapeutic approaches for cancer patients.

پروفایل رسمی دانشگاه

Rytis Jurkonisمشاهده پروفایل

پژوهشگر ارشد

Kaunas University of TechnologyLithuania

Rytis Jurkonis is a Research Fellow at the Institute of Biomedical Engineering, Kaunas University of Technology (KTU), where he has been employed since 2000. He teaches clinical engineering modules in the Department of Electronics Engineering and conducts research at the intersection of ultrasound physics and biomedical applications. His academic credentials include: Bachelor of Electronics Engineering, KTU (1993) Master of Electronics Engineering, KTU (1995) PhD in Electrical and Electronics Engineering, Technology Sciences, KTU (2000) Jurkonis specializes in ultrasound wave-tissue interaction modeling, ultrasonic biomedical signal processing, and clinical engineering methodologies. His work develops electronic technologies for biological and medical applications, particularly focusing on non-invasive diagnostic systems and therapeutic enhancement through microbubble cavitation. Recent efforts target improving ultrasound-based tissue characterization and drug delivery efficiency. Analysis of his 2012-2017 publications reveals consistent innovation in ultrasound elastography for tissue elasticity measurement, microbubble-mediated sonoporation for drug delivery, and RF signal processing for ocular diagnostics. His research bridges engineering principles with clinical practice, emphasizing quantitative metrics for therapeutic efficacy and diagnostic accuracy in biomedical systems. He has secured significant research funding including the Eurostars NICDIT project (2008-2011) for non-invasive eye tumor diagnosis, and two Lithuanian Research Council projects: MIP 119/2010 on electroporation-enhanced drug delivery (2010-2012) and MIP 034/2013 on microbubble cavitation parameters for sonoporation efficiency (2013-2015). International collaboration features prominently in his work through research stints at Lund University and Linkoping University in Sweden. His methodology integrates laboratory experimentation with computational modeling to advance biomedical ultrasound applications, with publications appearing in Ultrasound in Medicine & Biology, Molecular Pharmaceutics, and Archives of Acoustics.

پروفایل رسمی دانشگاه

John Kheirمشاهده پروفایل

دانشیار

Boston Children's HospitalUnited States

John Kheir is an Associate Professor of Pediatrics at Harvard Medical School and a Senior Associate Cardiologist in the Department of Cardiology at Boston Children’s Hospital. He co-founded and leads the Translational Research Lab within the Heart Center, focusing on oxygen deprivation solutions and critical care innovations. Education: University of Virginia (Undergraduate and Medical School), Cincinnati Children's Hospital (Internship), Cincinnati Children's Hospital (Residency), Boston Children's Hospital (Fellowship). His research spans oxygen delivery systems , congenital heart disease , and critical care metrics . Notable work includes injectable oxygen microparticles , machine-learning models for ICU risk prediction , and hemodynamic monitoring tools . Recent publications explore hemorrhagic shock resuscitation , social determinants of ECMO outcomes , and pediatric sedation protocols . Key clinical interests include postoperative cardiac care , hypoplastic left heart syndrome , and innovative diagnostics . His lab develops real-time oxygen delivery devices and investigates neurological injury prevention during circulatory arrest.

پروفایل رسمی دانشگاه

Margaret A. Wheatleyمشاهده پروفایل

استاد

Drexel UniversityUnited States

Margaret A. Wheatley serves as the John M. Reid Professor at Drexel University's School of Biomedical Engineering, Science and Health Systems. She earned her BS and MS in Chemistry and Biochemistry from Oxford University before completing her PhD in Chemical Engineering at the University of Toronto. Following postdoctoral research with Dr. Robert Langer at MIT and three years in industry at Glaxo Smith Kline, she joined Drexel in 1987 as the Chemical Engineering Department's first female faculty member, then became an inaugural faculty member in the School of Biomedical Engineering in 1998. Dr. Wheatley's research centers on developing novel polymeric platforms for medical applications, with particular focus on ultrasound contrast agent development for imaging, tumor targeting, and triggered drug delivery systems. Her laboratory has pioneered approaches to oxygen delivery to hypoxic tissue using ultrasound-sensitive carriers and developed innovative methods for spinal cord injury repair through encapsulated cell therapy. Her work integrates materials science, drug delivery, and ultrasound technology to address critical medical challenges. Analysis of her recent publications reveals a strong trend toward multimodal imaging approaches and targeted cancer therapies, with significant emphasis on polymeric microbubbles that can be activated at specific anatomical locations to release therapeutic agents. This technology enables precise drug delivery to tumors while minimizing systemic side effects, representing a significant advancement in cancer treatment modalities. Her scientific contributions have been recognized with awards including the W.W. Smith Charitable Trust Research Award (2015) and an NIH National Cancer Institute Grant for her oxygen microbubbles project. She has also moderated high-profile academic discussions, including a Science Unscripted Talk with Robert Langer in 2021. Dr. Wheatley has mentored numerous students throughout her career, with current PhD candidates Lauren Jablonowski, Brian Oeffinder, and Nutte Teraphongphom continuing her research legacy. Her laboratory, located in the Calhoun Comparative Medicine Laboratories at Drexel University, functions as a diverse interdisciplinary team working at the interface of biotechnology and materials science, with current projects including controlling stem cell differentiation with materials and developing novel polymers for biomedical applications.

پروفایل رسمی دانشگاه

Roger Zempمشاهده پروفایل

دانشیار

University of AlbertaCanada

Roger Zemp serves as an Associate Professor in the Department of Electrical and Computer Engineering within the Faculty of Engineering at the University of Alberta, concurrently holding an Adjunct Assistant Professor appointment in the Department of Biomedical Engineering. His academic profile spans advanced biomedical imaging research and specialized graduate instruction. Dr. Zemp's educational foundation includes: BSc in Physics from the University of Alberta (1998) MSc in Electrical & Computer Engineering from the University of Toronto (2000) PhD in Biomedical Engineering from the University of California, Davis (2004) His pioneering research develops novel biomedical imaging modalities to address unmet clinical needs, focusing on high-resolution optical-contrast techniques and therapeutic applications. Current projects integrate engineering precision with biological complexity: Capacitive Micromachined Ultrasound Transducers (CMUTs) for 3D imaging and therapy Photoacoustic imaging of hemoglobin saturation, tumor angiogenesis, and nanoparticle agents Ultrasound-triggered biomarker liberation for disease localization Lipid-microbubble systems for targeted cancer drug/gene delivery SERS nanoparticle-based multiplexed molecular imaging Ultra-high-frame-rate ultrasound for cardiac dynamics analysis Dr. Zemp actively mentors graduate students and secures research funding for translational projects, though specific advisees and grant details remain unlisted in available materials. His laboratory infrastructure within the Donadeo Innovation Centre enables microfabrication, optical system development, and preclinical validation, fostering cross-disciplinary collaboration between engineering and medical researchers.

پروفایل رسمی دانشگاه

Hemaka Bandulasenaمشاهده پروفایل

دانشیار

Loughborough UniversityUnited Kingdom

Hemaka Bandulasena is a Reader in Chemical Engineering and Head of the Department of Chemical Engineering at Loughborough University's School of Aeronautical, Automotive, Chemical and Materials Engineering. His academic journey began with a BSc Eng (Hons) from the University of Moratuwa, Sri Lanka, followed by a PhD in 'Microfluidic Inference of Rheology of Complex Fluids' from the University of Sheffield in 2008. After three years as a post-doctoral researcher at Sheffield, he joined Loughborough University in 2012 as a lecturer, progressing to Senior Lecturer in 2016, Reader in 2022, and Head of Department in 2025. He previously served as Director of Doctoral Programmes from 2019-2022. BSc Eng (Hons), University of Moratuwa, Sri Lanka PhD, University of Sheffield, UK (2008) ILM Level 3 Award in Coaching ILM Level 5 Award in Leadership and Management His research focuses on sustainable chemical engineering solutions, particularly in microfluidics, biofuel production, and plasma-assisted biomass processing. Key research groups include Net Zero, Biotechnology and Healthcare, and Sustainable Manufacturing and Circular Economy. His work bridges fundamental fluid dynamics with practical applications in renewable energy and waste valorization. Analysis of his 15 most recent publications (2021-2025) reveals a strong emphasis on microbubble technology for bioethanol production, plasma-based pretreatment of lignocellulosic biomass, and fundamental studies of gas-liquid interfaces. His research consistently targets process intensification for sustainable manufacturing, with recurring themes in continuous processing, thermophilic fermentation, and novel reactor design for renewable energy applications. Senior Moulton Medal (2009) - Best paper published by IChemE Hemaka Bandulasena holds multiple professional affiliations including Chartered Engineer, Fellow of the Institution of Chemical Engineers, and Fellow of the Higher Education Academy. His collaborative network spans 50+ co-authors across institutions including University of Sheffield, Stanford University, and Claude Bernard University Lyon 1. Current research focuses on biofuels and biochemicals with active laboratory work in microfluidics and plasma reactors.

پروفایل رسمی دانشگاه