جستجوی استاد راهنمای دانشگاهی

Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.

• Systems Biology
• Synthetic Biology
• Genome Engineering
• +۱۷ مورد دیگر

Richard M. Murray is the Thomas E. and Doris Everhart Professor of Control and Dynamical Systems and Bioengineering at the California Institute of Technology (Caltech). He holds a B.S. from Caltech (1985), M.S. from UC Berkeley (1988), and Ph.D. from UC Berkeley (1990). He has served in academic roles from Assistant Professor (1991–1997) to his current endowed professorship. He chaired the Engineering and Applied Science division (2000–2005) and Biology and Biological Engineering (2020–2024). His research focuses on feedback control in biological and autonomous systems, synthetic cells, and networked control systems. Collaborators include experts in robotics, synthetic biology, and systems biology. Key awards include the IEEE Control Systems Award and election to the National Academy of Engineering. His educational contributions span courses on control systems, robotics, and bioengineering. Current research projects include the Developer Cell initiative (Sloan Foundation), layered testing for autonomous systems (AFOSR), and microbiome-based environmental solutions (CHARMME, ARO). He advises numerous graduate students and postdocs, with notable alumni in academia and industry. Labs include facilities in Keck and Steele laboratories at Caltech. His work bridges control theory, synthetic biology, and autonomous systems to address societal challenges like environmental monitoring and safe autonomy.

• Control Theory
• Autonomous Vehicles
• Biological Circuit Design
• +۳ مورد دیگر

Jun Hyung Lee is a Visiting Assistant Professor in the Department of Environmental Biology at SUNY College of Environmental Science and Forestry (ESF). His research focuses on advancing forest tree improvement and conservation through molecular and synthetic biology approaches, with a particular emphasis on enhancing plant resilience to environmental stresses via beneficial microbial interactions. He teaches courses in plant biotechnology and tissue culture methods. Education includes a Ph.D. in Forest Genetics from Purdue University (USA), and M.S. and B.S. degrees in Plant Science from Seoul National University (South Korea). His work integrates cutting-edge genetic engineering techniques with ecological studies to address challenges in plant stress tolerance, symbiosis, and epigenetic regulation. Recent projects include identifying novel symbiosis pathways for thermotolerance and analyzing flooding tolerance in hybrid poplars. Publications highlight contributions to plant-microbe interaction research, synthetic biology applications, and genome editing epigenetic impacts. Collaborations span institutions like Oak Ridge National Laboratory and the University of Georgia, reflecting his transdisciplinary approach to plant science. Lee’s teaching emphasizes practical skills in biotechnology, bridging laboratory innovation with field applications.

• Plant Biotechnology
• Molecular Biology
• Synthetic Biology
• +۵ مورد دیگر

Ting Lu is an Associate Professor at the University of Illinois at Urbana-Champaign in the School of Biomedical and Translational Sciences, focusing on microbial synthetic biology and systems biology. Their research bridges biology, engineering, and physics to reprogram cellular functionalities through gene regulatory networks. Ph.D. in Biophysics, University of California at San Diego (2007) B.S. in Physics, Zhejiang University (2002) Ting Lu's work explores microbial ecosystems, synthetic gene circuits, and their applications in biotechnology and medicine. By combining experimental approaches with mathematical modeling, they investigate bacterial communication networks, metabolic pathways, and spatial dynamics in microbial communities. Selected research trends include microbial consortia engineering for bioremediation and bioproduction, complexity reduction in microbiomes, and predictive modeling of synthetic gene networks. Their publications span high-impact journals such as Nature Communications , Nature Chemical Biology , and eLife . Fellow, American Institute for Medical and Biological Engineering (2022) Future Insight Prize (2021) Donald Biggar Willett Faculty Scholar (UIUC) (2020) NIH Maximizing Investigators' Research Award (2019) NSF CAREER Award (2015) AHA National Scientist Development Grant (2012) Ting Lu's lab has received grants from NIH, NSF, ONR, and industry partners. They offer undergraduate research opportunities in synthetic and systems biology, and teach advanced courses such as BIOE 430 - Intro Synthetic Biology and BIOE 432 - Systems Biology .

• Synthetic Biology
• Systems Biology
• Quantitative Biology
• +۵ مورد دیگر

David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.

• Natural Products Chemistry
• Medicinal Chemistry
• Biosynthesis
• +۴ مورد دیگر

Professor Daniel Segrè is a faculty member at Boston University, holding the title of Professor of Biology, Bioinformatics, and Biomedical Engineering. His research focuses on systems biology, microbial ecology, and metabolic engineering, with an emphasis on understanding complex biological networks and their applications in bioenergy and biomedicine. Segrè leads the Segre Lab ( segrelab.bu.edu ), where theoretical and computational approaches are applied to study metabolism, microbial interactions, and synthetic biology. Segrè earned his PhD from the Weizmann Institute of Science, Israel. His work bridges fundamental science and applied engineering, addressing topics such as microbial community dynamics, metabolic pathway design, and environmental microbiome applications. Research Interests: Systems biology of metabolism, evolution of biochemical networks, microbial interactions, bioinformatics, and environmental microbiome engineering. His lab develops computational models (e.g., COMETS) to simulate microbial ecosystems and design synthetic microbial communities for climate change mitigation and bioenergy production. Teaching: Courses include BE 777 (Computational Genomics), BF 821 (Bioinformatics Seminar), and BF 571 (Dynamics and Evolution of Biological Networks). These courses reflect his expertise in integrating computational methods with biological systems analysis.

• Systems Biology
• Metabolic Engineering
• Microbial Ecology
• +۷ مورد دیگر

Dr. Monica E. McCallum is an Assistant Professor of Chemistry in the Department of Chemistry at the University of Pennsylvania’s School of Arts & Sciences. Her research focuses on understanding the biochemical origins of natural products and their roles in microbial communication. She leads the McCallum Lab, which employs interdisciplinary approaches combining organic synthesis, biochemistry, microbiology, and microscopy to study microbial natural products in their native contexts. Education: 2016 – Postdoctoral Fellow at Harvard University under Prof. Emily P. Balskus 2016 – PhD in Organic Chemistry from Baylor University 2013 – PhD Candidate at Colorado State University 2011 – B.S. in Chemistry from University of California, Irvine Research Interests: Dr. McCallum’s work bridges organic synthesis and microbiology to decode microbial metabolite functions. Key themes include: Synthesizing complex natural products and their biosynthetic precursors Discovering novel enzyme-catalyzed reactions Unraveling microbial communication mechanisms via natural products Investigating environmental microbial community dynamics Lab & Collaborations: The McCallum Lab emphasizes interdisciplinary collaboration, integrating techniques from organic chemistry, molecular biology, and microscopy to study natural products in situ. Current projects focus on diazeniumdiolate biosynthesis pathways and enzymatic detoxification of marine toxins.

• Microbial Chemistry
• Natural Products Synthesis
• Biochemistry
• +۳ مورد دیگر

Paul O'Toole is a Professor of Microbial Genomics and Principal Investigator at the APC Microbiome Ireland, University College Cork. His research focuses on the gut microbiome's role in health, aging, and disease, particularly in the context of diet and probiotics. He leads projects like the ELDERMET study on elderly nutrition and the NU-AGE project exploring Mediterranean diets' anti-aging effects. He holds a BA (Mod.) from Trinity College Dublin and a PhD from Lund University, with postdoctoral training in Canada and New Zealand. Key grants include studies on dairy-derived microbiota, probiotic strain improvement, and microbiome analysis in aging populations. He has published extensively on Lactobacillus genomics, gut-brain interactions, and microbiome-driven health outcomes. His work bridges fundamental microbiology with clinical applications, emphasizing translational research. Scientific highlights include discovering microbiome links to cognitive decline, demonstrating dietary modulation of gut microbes to combat obesity, and identifying keystone species in healthy aging. He advocates for sustainability in conservation and food systems, reflecting his interdisciplinary approach to global health challenges.

• Microbial Genomics
• Gut Microbiome
• Aging and Healthy Aging
• +۴ مورد دیگر

Dr. Jeremy Guest is the Levenick Professor in Civil and Environmental Engineering (and courtesy appointment in Chemical & Biomolecular Engineering) at the University of Illinois Urbana-Champaign (UIUC). He serves as Associate Director for Research at the Institute for Sustainability, Energy, and Environment (iSEE) and leads the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI). His research focuses on advancing circular bioeconomies through sustainable sanitation systems, resource recovery from wastewater, and biofuel/bioproduct development from lignocellulosic biomass. Guest's work emphasizes Quantitative Sustainable Design (QSD) methodologies to bridge engineering innovation with policy and investment decisions. Education: PhD in Environmental Engineering (University of Michigan, 2012); MS (Virginia Tech, 2007); BS (Bucknell University, 2005). Research interests include wastewater treatment innovation, nutrient recovery, bioenergy systems design, and sustainable agriculture practices. Key contributions include the EcoRecover phosphorus recovery process, the QSDsan modeling platform, and leadership in CABBI's $262.5M DOE-funded initiative. Guest has secured funding from NSF, US EPA, USDA, and the Bill & Melinda Gates Foundation. Recognitions include the NSF CAREER Award, 2021 James J. Morgan Early Career Award, and the Paul L. Busch Award. He advises over 15 graduate students and leads multiple high-impact projects like the NEWgenerator sanitation system and oilcane biorefinery integration. Lab/Group: Guest Research Group focuses on experimental, computational, and policy-oriented research to solve global sustainability challenges. Current projects address algae-based wastewater treatment, fecal sludge management in low-income regions, and precision fermentation systems development.

• Circular Bioeconomy
• Wastewater Treatment
• Resource Recovery
• +۵ مورد دیگر

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +۴ مورد دیگر

Lauren Andrews serves as Associate Professor and Marvin and Eva Schlanger Faculty Fellow in the Department of Chemical Engineering at the University of Massachusetts Amherst. Her research integrates synthetic biology and genetic engineering to develop programmable cellular systems for biotechnological applications. Education: Postdoctoral Training: Massachusetts Institute of Technology (Biological Engineering and Broad Institute of MIT and Harvard) PhD: University of Colorado Boulder, Chemical Engineering (2012) MS: University of Colorado Boulder, Chemical Engineering (2009) BS: Cornell University, Chemical Engineering (2006) Dr. Andrews' research focuses on establishing genetic design rules for reprogramming cellular regulation and metabolism. Her lab pioneers synthetic gene networks, genetically-encoded biosensors, and high-throughput methodologies for optimizing genetic designs in both model and non-model bacteria. This work enables precise control of cellular sensing, memory, and environmental responses through multiplexed DNA assembly and next-generation sequencing. Analysis of her 15 most recent publications reveals dominant themes in bacterial biosensor development (particularly for bioremediation), quorum sensing engineering, and programmable genetic circuits for probiotic applications. Her research consistently bridges fundamental genetic circuit design with practical implementations in bacterial consortia and non-model organisms. Scientific Awards: Marvin and Eva Schlanger Faculty Fellowship NSF CAREER Award (2020) for "Programmable synthetic microbial consortia for complex multicellular functions" Her grant portfolio demonstrates significant funding for collaborative research in bacterial communication systems and model-guided design of synthetic ecosystems. The Andrews Lab maintains active partnerships with the MIT-Broad Foundry and Cold Spring Harbor Laboratory, where she co-founded the Synthetic Biology Summer Course. Current projects focus on CRISPR-based regulation in non-model bacteria and algorithmic programming of sequential logic in probiotic strains. The Andrews Lab operates within the Life Science Laboratories at UMass Amherst, utilizing advanced facilities for genetic prototyping and high-throughput screening. Her team develops multiplexed tools for exploring genetic design spaces, with particular emphasis on soil bacteria and Gram-positive pathogens for environmental and therapeutic applications.

• Synthetic Biology
• Genome Engineering
• Metabolic Engineering
• +۵ مورد دیگر

Karoline Faust is an Associate Professor at KU Leuven, affiliated with the Laboratory of Molecular Bacteriology (Rega Institute) and the Faculty of Medicine . She contributes to the iSi Health and Leuven One Health institutes, and serves on senior academic councils. Her research spans microbial systems biology, focusing on community dynamics and network analysis. Education: PhD in bioinformatics (2010, KU Leuven) Affiliations: KU Leuven, ISME Journal editorial board, Belgian Society for Microbiology Her research investigates microbial community dynamics , systems biology approaches to microbiomes, and bioinformatics tool development . She specializes in modeling human gut microbiota , synthetic microbial communities , and environmental microbiomes (e.g., microplastic impacts on Daphnia microbiomes). Her work integrates metabolic modeling , network analysis , and experimental systems to understand microbial interactions. Recent publications highlight her contributions to microbial network inference , 16S rRNA sequencing protocols , microfluidics , and ecological modeling of microbiomes. She develops tools like manta , miaSim , and CoNet to analyze community structures. Teaching: Karoline co-teaches courses in microbiology, bioinformatics, and network analysis at KU Leuven, and has contributed to international workshops on microbial network inference. Scientific Engagement: She serves as Senior Editor at ISME Journal and Secretary of the Belgian Society for Microbiology .

• Microbial community dynamics
• Microbial systems biology
• Bioinformatics
• +۶ مورد دیگر

Josh Atkinson is an Assistant Professor in the Department of Civil and Environmental Engineering and the Omenn-Darling Bioengineering Institute at Princeton University. His research focuses on using synthetic biology and protein engineering to control electron transport in microbes for environmental applications, such as bioelectronic sensors and bioremediation. The Atkinson Lab investigates microbial energy processing, biofilm-electronic interfaces, and sustainable biotechnologies. Affiliations: Princeton University, Omenn-Darling Bioengineering Institute Research Interests: Microbial electron transport, bioelectronic systems, environmental monitoring, sustainable catalysis His work bridges disciplines like electrochemistry, bioengineering, and environmental science to engineer living materials for real-world challenges. The lab recruits students across levels, emphasizing diversity and interdisciplinary collaboration. Recent projects include real-time contaminant sensors and light-controlled biofilm patterning. Articles highlight innovations in bioelectronics and microbial systems engineering. The lab’s future directions involve scaling-up bioelectronic devices and enhancing microbial community understanding.

• Synthetic Biology
• Protein Engineering
• Electrochemistry
• +۷ مورد دیگر

Jonathan Conway is an Assistant Professor in the Department of Chemical and Biological Engineering at Princeton University and an associated faculty member of the High Meadows Environmental Institute (HMEI). He leads the Conway Lab, which focuses on engineering plant-microbe interactions for applications in bioagriculture, bioenergy, and biochemical industries. Education: B.S. Chemical Engineering, University of Notre Dame (2011) M.S. Chemical Engineering, North Carolina State University (2013) Ph.D. Chemical Engineering, North Carolina State University (2017) Postdoctoral Fellow, University of North Carolina Chapel Hill & Howard Hughes Medical Institute (2017-2021) Research Interests: The Conway Lab develops genetic engineering approaches for non-model bacteria at plant-microbe interfaces. Key research areas include: chemical signaling between plants and microbes, microbiome impacts on plant immunity, environmental stress responses in agricultural systems, and enzymatic degradation of lignocellulosic biomass using thermophilic bacteria. The lab employs bacterial genetics, systems biology, and biomolecular engineering to create technologies for sustainable bioindustries. Publication Trends: Recent work demonstrates strong emphasis on molecular mechanisms of plant-microbe communication (2020-2024), enzyme characterization in biomass degradation (2024-2025), and development of synthetic microbial communities for climate resilience (2024). Earlier research focused on extremophile enzymology and metabolic engineering (2012-2019). Student Advising: Currently mentors 4 graduate students and 8 undergraduates. Alumni include 9 former advisees who graduated between 2022-2024. The lab actively recruits students through Princeton's Chemical Engineering graduate program and undergraduate research initiatives. Laboratory: The Conway Lab develops microfluidic systems for root microbiome studies and genetic tools for engineering plant-associated bacteria. Current projects include designing thermophilic microbial consortia for consolidated bioprocessing and characterizing bacterial immune evasion strategies.

• Plant-microbe interactions
• Biomolecular engineering
• Systems biology
• +۴ مورد دیگر

Dr. Michael Baym is an Associate Professor of Biomedical Informatics at Harvard Medical School with affiliate appointments in Microbiology and the Laboratory of Systems Pharmacology, and as an Associate Member of the Broad Institute. He leads the Baym Lab, which studies microbial evolutionary genomics and antibiotic resistance through a hybrid of experimental, computational, and theoretical approaches. His research focuses on: Antibiotic Resistance Evolution and practical interventions Mobile Genetic Elements (plasmids, phages, transposons) Computational Genomic Algorithms for big data analysis Synthetic Biology tools and technologies Key recent publications explore phage discovery systems , phylogenetic compression of microbial genomes, and RNA-guided gene drives in plasmids. His work is supported by multiple NIH/NIGMS and NSF grants including a MIRA award. Scientific honors include: Packard Fellowship (2018) Pew Biomedical Scholarship (2020) Sloan Research Fellowship (2020) A. Clifford Barger Excellence in Mentoring Award (2021) SSQBio Mentorship Award (2022) The lab actively trains PhD students and postdoctoral fellows with alumni occupying academic and industry positions globally. Current team members include researchers from interdisciplinary backgrounds working at the intersection of experiment, computation, and theory .

• Microbial Evolutionary Genomics
• Antibiotic Resistance
• Computational Biology
• +۷ مورد دیگر